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This guideline covers identifying and treating primary hypertension (high blood pressure) in people aged 18 and over, including people with type 2 diabetes. It aims to reduce the risk of cardiovascular problems such as heart attacks and strokes by helping healthcare professionals to diagnose hypertension accurately and treat it effectively.
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This guideline includes recommendations on: 1. diagnosing hypertension 2. starting antihypertensive drug treatment 3. monitoring treatment and blood pressure targets 4. choosing antihypertensive drug treatment(treatment steps 1 to 4) 5. measuring blood pressure 6. assessing cardiovascular risk and target organ damage 7. lifestyle interventions
Healthcare professionalsCommissioners and providersPeople who have or may have high blood pressure, their families and carersHow we develop NICE guidelines This guideline updates and replaces NICE guideline CG127. It also updates and replaces the section on blood pressure management in the NICE guideline on type 2 diabetes in adults(NG28).
This guidance applies to adults with hypertension (18 years and older) including those with type 2 diabetes (replaces NICE guideline CG87) and chronic kidney disease (CKD) (see NICE guideline CG182). Hypertension is one of the most important preventable causes of premature morbidity and mortality in the UK.
- About amlodipine. Amlodipine is a medicine used to treat high blood pressure (hypertension). If you have high blood pressure, taking amlodipine helps prevent future heart disease, heart attacks and strokes.
- Key facts. Amlodipine lowers your blood pressure and makes it easier for your heart to pump blood around your body. It's usual to take amlodipine once a day.
- Who can and cannot take amlodipine. Amlodipine can be taken by adults and children aged 6 years and over. Amlodipine is not suitable for some people. To make sure amlodipine is safe for you, tell your doctor if you
- How and when to take it. Take amlodipine exactly as your doctor has told you, and follow the directions on the label. If you're not sure, check with your doctor or pharmacist.
STEP 1 Prescribe: Calcium channel blocker (CCB) (eg. amlodipine 5mg daily) • If BP remains above target , increase dose after 2-4 weeks to 10mg daily if tolerated • Side effects include flushing and headaches at initiation; swollen ankles especially at higher doses
Amlodipine starts to work on the day you start taking it, but it may be a couple of weeks before it takes full effect. If you're taking amlodipine for high blood pressure, you may not have any symptoms. In this case, you may not feel any different when you take amlodipine.
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Management of Hypertension using ABPM. Based on NICE NG136 Hypertension in adults: diagnosis and management (2019). Ambulatory Blood Pressure Monitoring (ABPM) is the preferred method of diagnosis because of its accuracy. If ABPM is unsuitable or the person is unable to tolerate it, offer home blood pressure monitoring (HBPM) to confirm the ...
