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Discover a natural way to correct high blood pressure naturally. so you’ll never have to suffer the horrendous side effects again
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- By blocking calcium from entering the blood vessel walls It reduces fat in the bloodstream By causing the kidneys to add more salt and water to the urine
palsforhealth.com/Pals/Article/How does amlodipine work
People also ask
Does amlodipine lower blood pressure?
Can you take amlodipine for a long time?
How does amlodipine work?
Does amlodipine cause fatty liver disease?
Does amlodipine change the levels of calcium in the blood?
How does amlodipine work in angina?
Eat well – aim to eat a diet that includes plenty of fruit and vegetables, wholegrains, fat-free or low-fat dairy products, and lean proteins. It's a good idea to follow these tips for a lower salt diet , too.
- What foods will make my high cholesterol worse? If you have high cholesterol, it’s most important to eat less saturated fat. Foods that are high in saturated fats are things like fatty and processed meat, pies and pastry, butter, cream, and coconut oil.
- What foods will lower my cholesterol? The best way to eat a better diet is to swap your saturated fats with foods that are high in unsaturated fat like vegetable oils (sunflower, olive and rapeseed oil), nuts seeds and avocado and oily fish.
- Can exercise help to lower cholesterol? Yes it can. Getting your blood pumping by doing exercise will reduce your cholesterol. Being active helps your body move the bad cholesterol to your liver where it can be removed out of your system.
- Will stopping smoking lower my cholesterol? If you're a smoker you might already know you should stop if you have high cholesterol. Smoking increases ‘bad cholesterol’ and lowers ‘good cholesterol’, increasing your risk of heart attacks and stroke.
- Overview
- How does amlodipine affect the liver?
- Can amlodipine cause liver damage?
- Can amlodipine cause fatty liver disease?
- Can amlodipine help people with fatty liver disease?
- Is amlodipine safe for people with fatty liver disease?
- Is amlodipine safe for people with other types of liver disease?
- Takeaway
Amlodipine is a medication that doctors prescribe to treat high blood pressure and reduce chest pain. Pharmacies in the United States fill millions of amlodipine prescriptions every year.
While taking amlodipine can be good for your heart health, some people may be concerned about its side effects, including potential liver damage.
Your liver contains enzymes that break down other proteins so your body can absorb them. It helps turn food into energy and removes toxins from your body.
These enzymes also break down many medications, including amlodipine. Cytochrome p450 enzymes break down amlodipine into its parts. This enables amlodipine to work in your body and for your body to then discard the waste portions.
Damage to your liver can cause it to release some enzymes into your bloodstream. Recent research has shown that amlodipine can cause levels of the enzymes aspartate aminotransferase (AST) and alanine aminotransferase (ALT) to increase. This suggests that amlodipine may cause drug-induced liver injury.
Researchers don’t quite know how amlodipine may cause liver injury. As the liver breaks amlodipine down, it may form a toxic compound.
People who take amlodipine may experience a mild elevation in their liver enzymes. This usually goes away quickly and doesn’t cause any significant symptoms or effects.
Few case reports exist that connect amlodipine to liver damage. Researchers estimate that liver damage due to any medication occurs in about 14 to 19 per 100,000 people.
In the very few published reports, the liver injury typically occurred 1 to 3 months after starting to take amlodipine.
If a person does experience liver problems after taking amlodipine, they’ll typically have jaundice symptoms. These symptoms include a yellow tint to the skin, flu-like symptoms, and fever.
Fortunately, there are no reports of amlodipine causing long-term liver damage. Symptoms usually go away when you stop taking the medication.
If your liver is sensitive to amlodipine, you may be at increased risk of liver problems if you take other calcium channel blockers, such as nicardipine, diltiazem, or verapamil.
Nonalcoholic fatty liver disease (NAFLD) occurs when you have more fat than is typical in your liver. Too much fat can contribute to later liver damage. About 23% of people with fatty liver disease (both NAFLD and from alcohol use) have elevated liver enzymes.
Research has not shown amlodipine to contribute to NAFLD. In fact, according to a recent study in mice with NAFLD and hypertension, amlodipine seemed to be protective against NAFLD. You can read more about this in the next section.
Currently, there are no medications that treat NAFLD. But doctors often search for medications that may help reduce the risks of liver damage.
The researchers in the 2021 study on mice found amlodipine helped to reduce ALT enzymes as well as potential contributors to NAFLD, such as triglycerides and cholesterol.
The study found amlodipine improved lipid (fat) metabolism in mice. It promoted the growth of beneficial bacteria in the gut and the breaking down of compounds that otherwise lead to the progression of NAFLD.
While this is promising research, human trials will be needed before we know if amlodipine can have protective benefits against NAFLD.
Doctors often prescribe amlodipine to treat hypertension (high blood pressure). Research has also shown a link between high blood pressure and NAFLD.
So can people with NAFLD safely take amlodipine for high blood pressure?
While there are some reports of liver complications from amlodipine, they’re rare. And researchers still don’t know what causes the link.
For this reason, your doctor will likely consider it safe to prescribe amlodipine even if you have NAFLD.
People with liver disease can typically take amlodipine safely. Your doctor should review potential side effects related to taking amlodipine. These may include:
•dizziness
•fatigue
•headache
•heart palpitations
•nausea
Amlodipine is a medication that can help lower your blood pressure. While amlodipine can cause side effects, liver disease is an uncommon one.
One animal study also found taking amlodipine could potentially improve fatty liver disease.
- Rachel Nall, MSN, CRNA
Eating more fibre has been linked to a lower risk of heart and circulatory diseases. Soluble fibre from oats (called beta-glucans) may help in lowering blood pressure. A diet higher in fibre is advised if you are trying to lose weight, which will also help lower your blood pressure.
Jul 23, 2024 · Eating a diet rich in whole grains, fruits, vegetables and low-fat dairy products and low in saturated fat and cholesterol can lower high blood pressure by up to 11 mm Hg. Examples of eating plans that can help control blood pressure are the Dietary Approaches to Stop Hypertension (DASH) diet and the Mediterranean diet.
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- Alcohol can be both good and bad for your health. By drinking alcohol only in moderation — generally one drink a day for women, or two a day for me...
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Oct 3, 2023 · How it works. Amlodipine may be used to treat heart conditions such as angina and high blood pressure. Amlodipine inhibits the influx of calcium ions across cardiac (heart) and smooth muscle causing relaxation of these muscles and dilation (widening).
Jan 15, 2019 · What does current guidance say on this issue? NICE hypertension guidance updated in 2016 recommends the use of a calcium-channel blocker (such as amlodipine) in people over 55 years or in black people of African or Caribbean family origin of any age with high blood pressure.
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