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  1. Sep 10, 2024 · Remdesivir and nirmatrelvir/ritonavir (antiviral agents), baricitinib (an immunomodulatory drug), and 2 mRNA vaccines have gained full FDA approval for prevention and treatment of COVID-19...

  2. Sep 10, 2024 · See the article Coronavirus Disease 2019 (COVID-19) in Emergency Medicine. The Medscape article Acute Respiratory Distress Syndrome (ARDS) includes discussions of fluid management,...

  3. Feb 29, 2024 · Searching for effective therapies for COVID-19 infection is a complex process. Guidelines for COVID-19 have been published and continue to be revised as evidence emerges. [7, 8] The Milken...

    • Hypersensitivity
    • Clinical Worsening After Administration
    • Severe Covid-19
    • Viral Variants
    • Drug Interaction Overview
    Serious hypersensitivity reaction, including anaphylaxis, may occur
    Hypersensitivity reactions occurring more >24 hr after the infusion have also been reported with SARS-CoV-2 monoclonal antibodies under EUA
    If signs and symptoms occur, immediately discontinue IV infusion, and initiate appropriate medications and/or supportive care
    Infusion-related reactions reported, including fever, difficulty breathing, reduced oxygen saturation, chills, fatigue, arrhythmia (eg, atrial fibrillation, sinus tachycardia, bradycardia), chest p...
    Clinical worsening of COVID-19 after administration reported; signs or symptoms may include fever, hypoxia or increased respiratory difficulty, arrhythmia (eg, atrial fibrillation, sinus tachycardi...
    Some of these events required hospitalization
    Unknown if these events were related to the monoclonal antibodies or were due to progression of COVID-19
    Treatment benefit not observed in patients hospitalized with COVID-19
    Monoclonal antibodies may be associated with worse clinical outcomes when administered to hospitalized patients with COVID-19 requiring high-flow oxygen or mechanical ventilation
    Therefore, use is not authorized for use in patients
    Circulating SARS-CoV-2 viral variants may be associated with resistance to monoclonal antibodies
    Prescribing clinicians should consider prevalence of etesevimab resistant variants in their area
    Healthcare providers should review antiviral resistance information provided by state and local health departments
    Variant proportions circulating in the United States can be monitored at the CDC website
    Not renally excreted or metabolized by CYP450 enzymes
    Interactions with concomitant renally excreted drugs or drugs that are CYP450 substrates, inducers, or inhibitors are unlikely
  4. Jul 15, 2020 · Worldwide, scientists have launched over 1000 clinical trials of drugs for the treatment and prevention of SARS-CoV-2 since the start of January. Here's our very quick summary.

  5. Medscape's Pill Identifier helps you to ID generic and brand name prescription drugs, OTCs, and supplements. Search from over 10,000 tablets and capsules by imprint, color, shape, form, and...

  6. Mar 23, 2021 · This guideline covers managing COVID-19 in babies, children, young people and adults in community and hospital settings. It includes recommendations on communication, assessment, therapeutics for COVID-19, non-invasive respiratory support, preventing and managing acute complications, and identifying and managing co-infections.