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1. www.ncbi.nlm.nih.gov › pmc › articlesSynovial Sarcoma: A Clinical Review - PMC

   www.ncbi.nlm.nih.gov › pmc › articles

   May 19, 2021 · Synovial sarcoma is unique from other STS as it presents at a younger mean age of onset and commonly occurs in adolescents and young adults (mean age of 39 years at diagnosis) and affects both sexes equally . Synovial sarcoma is the most common non-rhabdomyosarcoma STS in children, representing 30% of STS diagnosed in childhood [4, 6].

   • Author: Aaron M. Gazendam, Snezana Popovic, Sohaib Munir, Naveen Parasu, David Wilson, Michelle Ghert
   • DOI: 10.3390/curroncol28030177

   • Publish Year: 2021
   • Publication: Curr Oncol. 2021 Jun; 28(3): 1909-1920.

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3. www.ncbi.nlm.nih.gov › pmc › articlesSystemic Treatment for Adults with Synovial Sarcoma

   www.ncbi.nlm.nih.gov › pmc › articles

   Mar 7, 2018 · Synovial sarcoma (SS) is a rare, yet highly malignant, type of soft tissue sarcoma (STS), for which survival has not improved significantly during the past years. In this review, we focus on systemic treatment in adults. Compared to other STS, SS are relatively chemosensitive.

   • Author: Ingrid M. E. Desar, Emmy D. G. Fleuren, Winette T. A. van der Graaf

   • Publish Year: 2018

4. www.mdanderson.org › cancerwise › synovial-sarcoma9 synovial sarcoma questions, answered - MD Anderson Cancer ...

   www.mdanderson.org › cancerwise › synovial-sarcoma

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   Aug 23, 2016 · Synovial sarcoma is one of the rarest cancers. Learn about common synovial sarcoma symptoms, treatment options and new clinical trial research in this Q&A.

   • Author: Devon Carter

5. www.esmoopen.com › article › S2059-7029(23)00853-0Synovial sarcoma: characteristics, challenges, and evolving ...

   www.esmoopen.com › article › S2059-7029(23)00853-0

   Aug 23, 2023 · Synovial sarcoma (SS) is a rare and malignant tumor of the connective tissues that presents challenges in diagnosis and treatment. 1,2 This article describes the epidemiology, clinical and genomic characteristics of SS, and the patient pathway from diagnosis to treatment.

6. link.springer.com › article › 10Synovial Sarcoma: Advances in Diagnosis and Treatment ...

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   Apr 10, 2017 · Synovial sarcoma is a malignant disease that frequently manifests in the extremities of young adults but can occur anywhere and in any age group. It has a tendency toward late recurrences and metastases, particularly in large tumors. Current multimodal treatment includes radiation, surgical resection, and chemotherapy.

   • Author: Marc El Beaino, Dejka M. Araujo, Alexander J. Lazar, Patrick P. Lin

   • Publish Year: 2017

7. www.ncbi.nlm.nih.gov › pmc › articlesSystemic Anti-Cancer Therapy in Synovial Sarcoma: A ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Nov 1, 2018 · Currently, there is no systemic anti-cancer therapy approved specifically for synovial sarcoma (SS). SS is an aggressive malignancy which accounts for approximately 5–10% of all STS [5,6,7,8]. The estimated incidence of SS is 1.5 per 1,000,000 in the US and 1.4 per 1,000,000 in the UK [7,9,10,11].

8. People also ask

   How common is synovial sarcoma (SS)?

   • Synovial sarcoma (SS) accounts for 5–10% of all STS [1, 2]. SS is an intriguing disease as, unlike the majority of STS, it can occur at any age and everywhere in the body. The peak incidence is in the 30s and it often presents in the extremities [3 •].

   Systemic Treatment for Adults with Synovial Sarcoma

   www.ncbi.nlm.nih.gov/pmc/articles/PMC5842271/

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   How is synovial sarcoma different from other STS?

   • Synovial sarcoma is unique from other STS as it presents at a younger mean age of onset and commonly occurs in adolescents and young adults (mean age of 39 years at diagnosis) and affects both sexes equally [ 5 ]. Synovial sarcoma is the most common non-rhabdomyosarcoma STS in children, representing 30% of STS diagnosed in childhood [ 4, 6 ]. 2.

   Synovial Sarcoma: A Clinical Review - PMC - National Center

   www.ncbi.nlm.nih.gov/pmc/articles/PMC8161765/

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   How is synovial sarcoma treated?

   • Synovial sarcomas have unique genomic characteristics and are driven by a pathognomonic t (X;18) chromosomal translocation and subsequent formation of the SS18:SSX fusion oncogenes. Surgical excision remains the mainstay of treatment with radiation therapy utilized in high-risk tumors.

   Synovial Sarcoma: A Clinical Review - PMC - National Center

   www.ncbi.nlm.nih.gov/pmc/articles/PMC8161765/

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   Can a synovial sarcoma tumor be removed?

   • The first surgery to remove a synovial sarcoma tumor may determine a patient’s prognosis. If the diagnosis was made after the tumor was removed, make sure the doctors got all the cancer out. If you’re still not confident, get a second opinion. How is synovial sarcoma typically treated?

   9 synovial sarcoma questions, answered - MD Anderson Cancer Center

   www.mdanderson.org/cancerwise/synovial-sarcoma.h00-159068712.html

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   What is the prognosis of synovial sarcoma?

   • Synovial sarcoma is a translocation-associated soft-tissue malignancy that frequently affects adolescents and young adults. It is driven by one of the fusion oncoproteins SS18-SSX1, SS18-SSX2, or rarely, SS18-SSX4. Prognosis of patients with recurrent or metastatic disease is generally poor, and newer therapeutic strategies are needed.

   Synovial Sarcoma: Advances in Diagnosis and Treatment

   link.springer.com/article/10.1245/s10434-017-5855-x

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   What is synovial sarcoma?

   • Synovial sarcoma is a relatively rare malignancy representing a soft tissue sarcoma (STS) of uncertain differentiation. It accounts for 5–10% of all STS [ 1, 2, 3 ].

   Synovial Sarcoma: A Clinical Review - PMC - National Center

   www.ncbi.nlm.nih.gov/pmc/articles/PMC8161765/

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9. www.esmoopen.com › article › S2059-7029(23)00853-0Synovial sarcoma: characteristics, challenges, and evolving ...

   www.esmoopen.com › article › S2059-7029(23)00853-0

   Aug 23, 2023 · Surgery with or without radiotherapy and/or chemotherapy can be effective in localized disease, especially in children. However, the prognosis in the advanced stages is poor, with treatment strategies that have relied heavily on traditional cytotoxic chemotherapies.