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1. www.ncbi.nlm.nih.gov › pmc › articlesSynovial Sarcoma: A Clinical Review - PMC

   www.ncbi.nlm.nih.gov › pmc › articles

   May 19, 2021 · The mainstay of treatment for synovial sarcoma remains surgical excision with negative margins with the addition of radiotherapy and/or chemotherapy based on patient and tumour characteristics .

   • Author: Aaron M. Gazendam, Snezana Popovic, Sohaib Munir, Naveen Parasu, David Wilson, Michelle Ghert
   • DOI: 10.3390/curroncol28030177

   • Publish Year: 2021
   • Publication: Curr Oncol. 2021 Jun; 28(3): 1909-1920.

2. www.ncbi.nlm.nih.gov › pmc › articlesSynovial sarcoma: characteristics, challenges, and evolving ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Aug 23, 2023 · Synovial sarcoma (SS) is a rare and malignant tumor of the connective tissues that presents challenges in diagnosis and treatment. 1,2 This article describes the epidemiology, clinical and genomic characteristics of SS, and the patient pathway from diagnosis to treatment.

   • DOI: 10.1016/j.esmoop.2023.101618
   • Published: 2023/10

   • Publication: ESMO Open. 2023 Oct; 8(5): 101618.

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4. www.ncbi.nlm.nih.gov › pmc › articlesSystemic Treatment for Adults with Synovial Sarcoma

   www.ncbi.nlm.nih.gov › pmc › articles

   Mar 7, 2018 · Synovial sarcoma (SS) is a rare, yet highly malignant, type of soft tissue sarcoma (STS), for which survival has not improved significantly during the past years. In this review, we focus on systemic treatment in adults. Compared to other STS, SS are relatively chemosensitive.

   • Author: Ingrid M. E. Desar, Emmy D. G. Fleuren, Winette T. A. van der Graaf

   • Publish Year: 2018

5. link.springer.com › article › 10Synovial Sarcoma: Advances in Diagnosis and Treatment ...

   link.springer.com › article › 10

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   Apr 10, 2017 · In this review, we present recent discoveries in the pathogenesis, diagnosis, and treatment of synovial sarcoma. We discuss potential therapeutic strategies to improve clinical outcomes in this disease.

   • Author: Marc El Beaino, Dejka M. Araujo, Alexander J. Lazar, Patrick P. Lin

   • Publish Year: 2017

6. www.researchgate.net › publication › 351732367(PDF) Synovial Sarcoma: A Clinical Review - ResearchGate

   www.researchgate.net › publication › 351732367

   May 19, 2021 · Synovial sarcomas (SS) represent a unique subset of soft tissue sarcomas (STS) and account for 5–10% of all STS. Synovial sarcoma differs from other STS by the relatively young age at...

7. link.springer.com › content › pdfSystemic Treatment for Adults with Synovial Sarcoma - Springer

   link.springer.com › content › pdf

   Synovial sarcoma (SS) is a rare, yet highly malignant, type of soft tissue sarcoma (STS), for which survival has not improved significantly during the past years. In this review, we focus on systemic treatment in adults. Compared to other STS, SS are relatively chemosensitive.

8. People also ask

   What is a synovial sarcoma?

   • Keywords: clinical review; current concepts; soft tissue sarcoma; synovial sarcoma. Synovial sarcomas (SS) represent a unique subset of soft tissue sarcomas (STS) and account for 5-10% of all STS. Synovial sarcoma differs from other STS by the relatively young age at diagnosis and clinical presentation.

   Synovial Sarcoma: A Clinical Review - PubMed

   pubmed.ncbi.nlm.nih.gov/34069748/

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   How common is synovial sarcoma (SS)?

   • Synovial sarcoma (SS) accounts for 5–10% of all STS [1, 2]. SS is an intriguing disease as, unlike the majority of STS, it can occur at any age and everywhere in the body. The peak incidence is in the 30s and it often presents in the extremities [3 •].

   Systemic Treatment for Adults with Synovial Sarcoma

   www.ncbi.nlm.nih.gov/pmc/articles/PMC5842271/

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   Is synovial sarcoma a subset of Sts?

   • Conclusions Synovial sarcomas (SS) represent a unique subset of STS and account for 5–10% of all STS. Synovial sarcoma differs from other STS by the relatively young age at diagnosis, anatomic location (peri-articular) and clinical presentation (slow-growing, painful lesions).

   Synovial Sarcoma: A Clinical Review - PMC - National Center

   www.ncbi.nlm.nih.gov/pmc/articles/PMC8161765/

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   How is synovial sarcoma treated?

   • Synovial sarcomas have unique genomic characteristics and are driven by a pathognomonic t (X;18) chromosomal translocation and subsequent formation of the SS18:SSX fusion oncogenes. Surgical excision remains the mainstay of treatment with radiation therapy utilized in high-risk tumors.

   Synovial Sarcoma: A Clinical Review - PMC - National Center

   www.ncbi.nlm.nih.gov/pmc/articles/PMC8161765/

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   Can pediatric adolescent patients with synovial sarcoma be treated without systemic therapy?

   • Recent data has demonstrated that pediatric or adolescent patients with low risk tumors (Grade 2 or Grade 3 < 5 cm) can be successfully treated with surgical intervention without systemic therapy [ 39 ]. The role of chemotherapy in adult patients with synovial sarcoma is less clear.

   Synovial Sarcoma: A Clinical Review - PMC - National Center

   www.ncbi.nlm.nih.gov/pmc/articles/PMC8161765/

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   How long does a synovial sarcoma last?

   • Synovial sarcomas often do not present with the typical STS presentation of a large and quickly growing painless mass [ 9 ]. Instead, the majority of synovial sarcomas are slow growing and the mean duration of symptoms before diagnosis is approximately 2 years [ 12 ].

   Synovial Sarcoma: A Clinical Review - PMC - National Center

   www.ncbi.nlm.nih.gov/pmc/articles/PMC8161765/

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9. pubmed.ncbi.nlm.nih.gov › 34069748Synovial Sarcoma: A Clinical Review - PubMed

   pubmed.ncbi.nlm.nih.gov › 34069748

   May 19, 2021 · Synovial sarcomas (SS) represent a unique subset of soft tissue sarcomas (STS) and account for 5-10% of all STS. Synovial sarcoma differs from other STS by the relatively young age at diagnosis and clinical presentation.