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    • Jacklyn Zeman. Jacklyn Zeman was a force to be reckoned with. Entering the daytime scene 1977, Zeman was among one of the longest-lasting cast members on "General Hospital," appearing in almost 900 episodes on and off for over 42 years.
    • Sonya Eddy. Sonya Eddy, who portrayed nurse Epiphany Johnson on "General Hospital," died on December 19, 2022. Eddy joined the cast of "General Hospital" in 2006 as the brutally honest but endearing nurse.
    • Billy Miller. The devastating death of actor Billy Miller shattered the daytime television community. Miller began his admirable career on the soap opera "Young and the Restless" as the character Billy Abbott, but "General Hospital" fans fondly remember him for his portrayal of Drew Cain.
    • Tyler Christopher. Tyler Christopher was long an essential part of the "General Hospital” family. He brought the character of Nikolas Cassadine to life through heartfelt acting that tugged on viewers heartstrings.
    • Lindsey Pearlman. Lindsey Pearlman played barista Margaret on "General Hospital" in 2020. Despite only appearing in a couple of episodes, she acted in some intense scenes, including getting caught up in a brutal shoot-out.
    • John Ingle. Playing duplicitous Edward Quartermaine, a role previously inhabited by David Lewis, John Ingle encapsulated the avarice of the formidable "General Hospital" antagonist.
    • Jay Pickett. Jay Pickett initially joined the "General Hospital" cast as Lorenzo Alcazar, before being cast in a permanent role as Detective David Harper in 2007.
    • Shell Kepler. A popular "General Hospital" star, Shell Kepler portrayed nurse Amy Vining for 23 years. Known for her wild flaxen locks and OTT makeup, Kepler perfectly embodied the gossipy nurse, not to mention '80s hairspray chic.
  1. May 30, 2024 · Following the brutal murder of actor Johnny Wactor, fans are reflecting on the numerous untimely and tragic deaths of cast members over the years.

    • Faye James
  2. Nov 2, 2023 · Even some Hollywood A-listers, such as Mark Hamill, Elizabeth Taylor, Ricky Martin, and Demi Moore, portrayed "General Hospital" characters. As the series has been on the air for so long,...

    • Looper Staff
  3. Jun 19, 2024 · General Hospital’s Jophielle Love Talks On Violet’s Emotional Scenes with Finn, the Loss of Gregory, and Taylor Swift. June 19, 2024. Photo: JPI. During General Hospital’s recent episodes surrounding the death of Gregory Chase (Gregory Harrison), who succumbed to complications from ALS, many in the cast delivered touching performances ...

  4. Jun 13, 2024 · Jeff Kober, who has starred as Cyrus Renault in 'General Hospital' since 2020, spoke with PEOPLE about how the recent cast member deaths have affected him, particularly when it’s time for him...

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  6. Jan 27, 2024 · Actor Tyler Christopher, best known for his years playing Nikolas Cassadine on General Hospital, died of suffocation affected by intoxication. Christopher died in October 2023 at the age of...