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    • Jacklyn Zeman. Jacklyn Zeman was a force to be reckoned with. Entering the daytime scene 1977, Zeman was among one of the longest-lasting cast members on "General Hospital," appearing in almost 900 episodes on and off for over 42 years.
    • Sonya Eddy. Sonya Eddy, who portrayed nurse Epiphany Johnson on "General Hospital," died on December 19, 2022. Eddy joined the cast of "General Hospital" in 2006 as the brutally honest but endearing nurse.
    • Billy Miller. The devastating death of actor Billy Miller shattered the daytime television community. Miller began his admirable career on the soap opera "Young and the Restless" as the character Billy Abbott, but "General Hospital" fans fondly remember him for his portrayal of Drew Cain.
    • Tyler Christopher. Tyler Christopher was long an essential part of the "General Hospital” family. He brought the character of Nikolas Cassadine to life through heartfelt acting that tugged on viewers heartstrings.
  1. May 11, 2023 · Following the news of Jacklyn Zeman's death, the actress' former General Hospital costars are flooding social media with tributes.

  2. May 30, 2024 · Following the brutal murder of actor Johnny Wactor, fans are reflecting on the numerous untimely and tragic deaths of cast members over the years.

    • Faye James
  3. Jun 13, 2024 · Jeff Kober, who has starred as Cyrus Renault in 'General Hospital' since 2020, spoke with PEOPLE about how the recent cast member deaths have affected him, particularly when it’s time for him...

  4. Nov 2, 2023 · But on June 29, 2021, a Facebook post from ABC entertainment reporter George Pennacchio announced the actor died at the age of 84 after "struggling with renal failure for the last several years."...

    • Looper Staff
  5. May 11, 2023 · Jacklyn Zeman, who played Bobbie Spencer for 45 years on ABC’s “General Hospital” has died at 70. Zeman died after a short battle with cancer, her family confirmed Wednesday.

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  7. Sep 29, 2023 · But the show's most notable IRL deaths are not confined to those who graced the grounds of Port Charles decades ago; many of the more recent cast members have sadly passed on.