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Apr 27, 2023 · The dosage of stimulants should be re-evaluated for drug-drug interactions as well as for side effects and changes in physiology with aging. Patients with impaired liver and renal function should be prescribed the lowest possible dose.
the initial recommendations depending on the severity of symptoms and the environmental demands of the person’s life. Medications that are FDA-approved specifically for ADHD in adults are the stimulants Adderall XR, Concerta, Focalin XR, Vyvanse, and the nonstimulant Strattera. The approved maximum age for use of these
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For ADHD core symptoms rated by clinicians in children and adolescents closest to 12 weeks, all included drugs were superior to placebo (eg, SMD –1·02, 95% CI –1·19 to –0·85 for amphetamines, –0·78, –0·93 to –0·62 for methylphenidate, –0·56, 0·66 to –0·45 for atomoxetine).
Aug 7, 2024 · In most cases, the maximum Adderall IR dosage for adults and children ages 6 years and older to treat ADHD is 40 mg daily. Your doctor will typically start you on a low dose and adjust it...
- Overview
- Attention Deficit Hyperactivity Disorder
- Narcolepsy
- Frequently asked questions
- More about Adderall (amphetamine / dextroamphetamine)
- Further information
Generic name: DEXTROAMPHETAMINE SACCHARATE 1.25mg, AMPHETAMINE ASPARTATE MONOHYDRATE 1.25mg, DEXTROAMPHETAMINE SULFATE 1.25mg, AMPHETAMINE SULFATE 1.25mg
Dosage form: tablet
Drug class: CNS stimulants
Regardless of indication, amphetamines should be administered at the lowest effective dosage, and dosage should be individually adjusted according to the therapeutic needs and response of the patient. Late evening doses should be avoided because of the resulting insomnia.
•for the presence of cardiac disease (i.e., perform a careful history, family history of sudden death or ventricular arrhythmia, and physical exam) (see WARNINGS).
•the family history and clinically evaluate patients for motor or verbal tics or Tourette’s syndrome before initiating Adderall® (see WARNINGS).
Not recommended for children under 3 years of age. In children from 3 to 5 years of age, start with 2.5 mg daily; daily dosage may be raised in increments of 2.5 mg at weekly intervals until optimal response is obtained.
In children 6 years of age and older, start with 5 mg once or twice daily; daily dosage may be raised in increments of 5 mg at weekly intervals until optimal response is obtained. Only in rare cases will it be necessary to exceed a total of 40 mg per day. Give first dose on awakening; additional doses (1 or 2) at intervals of 4 to 6 hours.
Where possible, drug administration should be interrupted occasionally to determine if there is a recurrence of behavioral symptoms sufficient to require continued therapy.
Prior to treating patients with Adderall® assess:
•for the presence of cardiac disease (i.e., perform a careful history, family history of sudden death or ventricular arrhythmia, and physical exam) (see WARNINGS).
•the family history and clinically evaluate patients for motor or verbal tics or Tourette’s syndrome before initiating Adderall® (see WARNINGS).
Usual dose 5 mg to 60 mg per day in divided doses, depending on the individual patient response.
Narcolepsy seldom occurs in children under 12 years of age; however, when it does, dextroamphetamine sulfate may be used. The suggested initial dose for patients aged 6 to 12 is 5 mg daily; daily dose may be raised in increments of 5 mg at weekly intervals until optimal response is obtained. In patients 12 years of age and older, start with 10 mg daily; daily dosage may be raised in increments of 10 mg at weekly intervals until optimal response is obtained. If bothersome adverse reactions appear (e.g., insomnia or anorexia), dosage should be reduced. Give first dose on awakening; additional doses (1 or 2) at intervals of 4 to 6 hours.
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Maximum dose: 40 mg once a day May increase after 3 days to target dose. Dose may be further increased to 100 mg per day after 2 to 4 additional weeks; dose may be given once a day in the morning or twice a day, evenly divided, in the morning and late afternoon or early evening.
PMCID: PMC2515906 PMID: 18728812. Abstract. This review focuses on the treatment of attention deficit hyperactivity disorder (ADHD) in adults. It briefly addresses prevalence, diagnostic and differential diagnostic issues specific to adults. Stimulant medication, non-stimulant medication, and psychosocial treatments are thoroughly reviewed.
