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Most patients have some mild sedation on guanfacine for the first 1-2 weeks, so it’s better to dose it at bedtime. Most patients habituate to the sedating effect within 2 weeks. Like beta-blockers, α2A-agonists have a mild anti-anxiety effect, very different from the other ADHD meds.
- Overview
- Attention Deficit Hyperactivity Disorder
- Narcolepsy
- Frequently asked questions
- More about Adderall (amphetamine / dextroamphetamine)
- Further information
Generic name: DEXTROAMPHETAMINE SACCHARATE 1.25mg, AMPHETAMINE ASPARTATE MONOHYDRATE 1.25mg, DEXTROAMPHETAMINE SULFATE 1.25mg, AMPHETAMINE SULFATE 1.25mg
Dosage form: tablet
Drug class: CNS stimulants
Regardless of indication, amphetamines should be administered at the lowest effective dosage, and dosage should be individually adjusted according to the therapeutic needs and response of the patient. Late evening doses should be avoided because of the resulting insomnia.
•for the presence of cardiac disease (i.e., perform a careful history, family history of sudden death or ventricular arrhythmia, and physical exam) (see WARNINGS).
•the family history and clinically evaluate patients for motor or verbal tics or Tourette’s syndrome before initiating Adderall® (see WARNINGS).
Not recommended for children under 3 years of age. In children from 3 to 5 years of age, start with 2.5 mg daily; daily dosage may be raised in increments of 2.5 mg at weekly intervals until optimal response is obtained.
In children 6 years of age and older, start with 5 mg once or twice daily; daily dosage may be raised in increments of 5 mg at weekly intervals until optimal response is obtained. Only in rare cases will it be necessary to exceed a total of 40 mg per day. Give first dose on awakening; additional doses (1 or 2) at intervals of 4 to 6 hours.
Where possible, drug administration should be interrupted occasionally to determine if there is a recurrence of behavioral symptoms sufficient to require continued therapy.
Prior to treating patients with Adderall® assess:
•for the presence of cardiac disease (i.e., perform a careful history, family history of sudden death or ventricular arrhythmia, and physical exam) (see WARNINGS).
•the family history and clinically evaluate patients for motor or verbal tics or Tourette’s syndrome before initiating Adderall® (see WARNINGS).
Usual dose 5 mg to 60 mg per day in divided doses, depending on the individual patient response.
Narcolepsy seldom occurs in children under 12 years of age; however, when it does, dextroamphetamine sulfate may be used. The suggested initial dose for patients aged 6 to 12 is 5 mg daily; daily dose may be raised in increments of 5 mg at weekly intervals until optimal response is obtained. In patients 12 years of age and older, start with 10 mg daily; daily dosage may be raised in increments of 10 mg at weekly intervals until optimal response is obtained. If bothersome adverse reactions appear (e.g., insomnia or anorexia), dosage should be reduced. Give first dose on awakening; additional doses (1 or 2) at intervals of 4 to 6 hours.
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Aug 7, 2024 · In most cases, the maximum Adderall IR dosage for adults and children ages 6 years and older to treat ADHD is 40 mg daily. Your doctor will typically start you on a low dose and adjust it...
Apr 27, 2023 · To minimize adverse effects, clinicians should start stimulants in older adults at the lowest dose and gradually increase until potential benefits are reached while monitoring for side effects. For example, methylphenidate can be started at 5 mg in the morning and then increased by 5 mg weekly based on the improvement of symptoms.
Aug 7, 2023 · The FDA sets the maximum for Adderall (IR or XR) at a dose of 40 mg/day for adult ADHD. However, they allow up to 60 mg/day for more severe cases of ADHD, as well as for narcolepsy. That 40–60 mg max was derived from a large registration trial of adult ADHD.
- Chris Aiken, MD
Nov 8, 2021 · These are the medications most people associate with ADHD: Ritalin, Adderall, Vyvanse, or Focalin (although there are many other names, as you will see below). The nonstimulants are Intuniv ...
Jan 28, 2021 · Key action statement 5b in the recent AAP “Clinical Practice Guideline for the Diagnosis, Evaluation, and Treatment of ADHD in Children and Adolescents” states that elementary school– and middle school–age children should be treated with a U.S. Food and Drug Administration (FDA)–approved medication, along with parent training in behavior managem...
