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Apr 17, 2021 · Hamish Mykura from West Hoathly near Haywards Heath took part in clinical trials after being diagnosed with an aggressive form of brain cancer.
Oct 18, 2021 · But by uncloaking the disease using ipatasertib, we could make some brain cancers vulnerable to atezolizumab.” Hamish Mykura, 59, was diagnosed with glioblastoma in August 2018 and joined the trial after chemotherapy and radiotherapy stopped working. Two years on, he has no visible cancer.
Apr 10, 2021 · Patient Hamish Mykura, 59, a TV producer from West Sussex, says he believed 2020 would be his last until scans revealed his brain cancer had all but vanished.
- 10 Patients Recruited to Ice-Cap Trial
- No Signs of Disease 22 Months Later
- 'Uncloaking The Disease'
- 'It's Astonishing That I'm Still Here'
So far, researchers have recruited 10 patients with glioblastoma who had relapsed after treatment to the Phase I Ice-CAP trial. Seven of them had tumours with defects in the PTEN gene and four patients had complete loss of PTEN expression. The trial, supported by the immunotherapy Centers Of Research Excellence (imCORE) network, a Roche academic-in...
One patient of the two patients who responded and had aggressive brain cancer with faulty PTEN genes, responded remarkably well to the drug combination – still showing no signs of disease 22 months later. Previous studies have suggested that defects in the PTEN gene weaken the anti-cancer immune response, reducing the ability of the immune system t...
Study leader Dr Juanita Lopez, Clinical Researcher at The Institute of Cancer Research, London, and Consultant Medical Oncologist at The Royal Marsden NHS Foundation Trust, said: “Brain cancer is able to evade the immune system in complex ways and, until now, immunotherapy has not worked. However, by uncloaking the disease using a new drug called i...
Hamish Mykura (59 from West Sussex) was first diagnosed with glioblastoma in August 2018 and was referred to The Royal Marsden for treatment, which included chemotherapy and radiotherapy, with surgery at St George's Hospital. When Hamish’s treatment stopped working and the cancer started to grow in August 2019, he joined the Ice-CAP trial. Some 20 ...
Hamish Mykura. Commissioner, Producer, Executive. 28 March 1962 to 27 March 2023. A British television executive, who spent more than a decade producing and commissioning for National Geographic, Channel 4 and the BBC.
Royal Marsden patient Hamish Mykura, 59, was diagnosed with glioblastoma in 2018 and joined the trial after traditional treatment, including chemotherapy and radiotherapy, stopped working. Over two years on, he has no visible cancer.
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Apr 11, 2021 · Patient Hamish Mykura, 59, a TV producer from West Sussex, says he believed 2020 would be his last until scans revealed his brain cancer had all but vanished. ‘The doctors are cautious but there’s a possibility I may be the first person to be cured of glioblastoma using drugs.’