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  1. Jan 1, 2022 · Studies on GERD treatment typically last only 8-12 weeks, in part because symptom relief and healing appear to peak in that time frame. The healing rates of erosive esophagitis are not linear; thus, clinicians and patients need to understand that symptom relief and healing may not be rapid.

    • 10.14309/ajg.0000000000001538
    • 2022/01/01
  2. Patients should receive an annual review of their condition. Patients on a long-term PPI for GORD should be encouraged to either step-down to the lowest effective dose to control symptoms, continue treatment on a when needed bases or stop treatment.

    • Recommendations
    • Who Is It for?
    • Guideline Development Process

    This guideline includes recommendations on: 1. referral for endoscopy 2. interventions for uninvestigated dyspepsia, GORD, peptic ulcer disease and functional dyspepsia 3. Helicobacter pylori testing and eradication 4. laparoscopic fundoplication 5. referral to specialist services 6. surveillance for people with Barrett’s oesophagus

    Healthcare professionals
    Commissioners and providers
    Adults with GORD or dyspepsia and their families

    How we develop NICE guidelines This guideline was previously called dyspepsia and gastro-oesophageal reflux disease: investigation and management of dyspepsia, symptoms suggestive of gastro-oesophageal reflux disease, or both.

  3. Non-drug treatment. Lifestyle measures, such as healthy eating, weight loss (if obese), avoiding trigger foods, eating smaller meals, eating the evening meal 3–4 hours before going to bed, raising the head of the bed, Smoking cessation, and reducing alcohol consumption may improve symptoms.

  4. Sep 3, 2014 · These recommendations apply to adults (aged 18 and over) with symptoms of dyspepsia, symptoms suggestive of gastro-oesophageal reflux disease (GORD), or both. In this guideline, GORD refers to endoscopically determined oesophagitis or endoscopy-negative reflux disease.

  5. May 30, 2024 · Gastro-oesophageal reflux disease (GORD) is a clinical diagnosis. The classic symptoms are heartburn and regurgitation. A therapeutic trial of a proton-pump inhibitor (PPI) can serve for both diagnosis and initial treatment.

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  7. Dec 1, 2022 · Adult patients with classic GERD symptoms of heartburn and regurgitation without alarm symptoms such as dysphagia, weight loss, bleeding, vomiting, anemia, and chest pain can be treated with an 8-week empiric trial of a PPI taken once daily before meals. An upper age limit is not specified.

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