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  2. Jun 21, 2024 · endoplasmic reticulum (ER), in biology, a continuous membrane system that forms a series of flattened sacs within the cytoplasm of eukaryotic cells and serves multiple functions, being important particularly in the synthesis, folding, modification, and transport of proteins.

    • Endoplasmic Reticulum Definition
    • Endoplasmic Reticulum Overview
    • Endoplasmic Reticulum Function
    • Structure of The Endoplasmic Reticulum
    • Endoplasmic Reticulum Location
    • Types of Endoplasmic Reticulum

    The endoplasmic reticulum (ER) is a large organelle made of membranous sheets and tubules that begin near the nucleus and extend across the cell. The endoplasmic reticulum creates, packages, and secretes many of the products created by a cell. Ribosomes, which create proteins, line a portion of the endoplasmic reticulum.

    The entire structure can account for a large proportion of the endomembrane system of the cell. For instance, in cells such as liver hepatocytes that are specialized for protein secretion and detoxification, the ER can account for more than 50% of the total lipid bilayer of the cell.Similarly, the ER membrane system is particularly prominent in pan...

    The ER plays a number of roles within the cell, from protein synthesis and lipid metabolism to detoxification of the cell. Cisternae, each of the small folds of the endoplasmic reticulum, are commonly associated with lipid metabolism. This creates the plasma membrane of the cell, as well as additional endoplasmic reticulum and organelles. They also...

    The endoplasmic reticulum membrane system can be morphologically divided into two structures–cisternae and sheets. Cisternae are tubular in structure and form a three-dimensional polygonal network.They are about 50 nm in diameter in mammals and 30 nm in diameter in yeast. ER sheets, on the other hand, are membrane-enclosed, two-dimensional flattene...

    The endoplasmic reticulum processes most of the instructions from the nucleus. As such, the endoplasmic reticulum surrounds the nucleus and radiates outward. In cells that secrete many products for the rest of the body, the endoplasmic reticulum can account for more than 50% of the cell. In general, the nucleus expresses mRNA (messenger RNA), which...

    There are two major types of ER within each cell – smooth endoplasmic reticulum (SER) and rough endoplasmic reticulum (RER). Each has distinct functions, and often, differing morphology. The SER is involved in lipid metabolism and acts as the calcium store for the cell. This is particularly important in muscle cells that need Ca2+ions for contracti...

    • Gabe Buckley
  3. The endoplasmic reticulum is the cell organelle that originates from the cell’s nuclear envelope, synthesizes protein, and transports the proteins for cellular metabolism. Depending on the cell, the endoplasmic reticulum can occupy 50% of the cell volume.

  4. Oct 31, 2023 · The endoplasmic reticulum (ER) is a series of interconnected membranous sacs and tubules that collectively modifies proteins and synthesizes lipids. However, these two functions are performed in separate areas of the ER: the rough ER and the smooth ER.

  5. The endoplasmic reticulum (ER), typically the largest membrane-bound organelle in a eukaryotic cell, plays a critical role in many cellular processes, including protein synthesis, protein modification, lipid synthesis and the regulation of Ca 2+ homeostasis and secretion [ 1 ].

    • Shuliang Chen, Peter Novick, Susan Ferro-Novick
    • 10.1016/j.ceb.2013.02.006
    • 2013
    • 2013/08
  6. Aug 3, 2023 · The SER is present in liver cells which stores the glycogen. Similarly, it is also found in interstitial cells, adrenal cortical cells of the kidney, adipose cells, muscle cells, and the retinal cell of an eye. The Smooth endoplasmic reticulum consists of the enzyme glucose-6-phosphatase.

  7. The endoplasmic reticulum (ER) is a network of membrane-enclosed tubules and sacs (cisternae) that extends from the nuclear membrane throughout the cytoplasm (Figure 9.1). The entire endoplasmic reticulum is enclosed by a continuous membrane and is the largest organelle of most eukaryotic cells.

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