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  1. The BoneXpert online Adult Height Predictor, www.BoneXpert.com/ahp underwent a major update on 12 Feb 2021 to version 3.0. This whitepaper gives the clinical background for the update, including its development and validation. The main improvements in version 3 are:

  2. Prediction of the Age of Peak Height Velocity (APHV) Visualisation of the most likely growth path in a growth chart including the corresponding height velocity curve. The method has been validated on normal, healthy children and on children with untreated idiopathic short stature.

  3. 20 peer-reviewed publications document the clinical evaluation, including studies the of the accuracy of adult height prediction based on bone age. Explained. BoneXpert explains the overall bone age as the averaging over the annotated bones, like a human rater would do.

    • Greulich-Plye (GP) Method
    • Tanner-Whitehouse-3 (TW3) Method
    • Bayley-Pinneau (BP) Method
    • Khamis-Roche Method
    • CDC Growth Charts
    • Online Height Calculators
    • Conclusion

    The Greulich and Pyle standards are the most widely used age estimation all over the world. They consist of two series of standard plates obtained from hand-wrist X-rays of white, upper-class boys and girls between 1931 and 1942. This method is simple and quick to carry out. The radiograph of the left hand to be assessed is compared with the series...

    Like the GP method, the Tanner-Whitehouse 3 (TW3) method uses left-wrist radiographs to determine the bone age. Radiographs of the hand and wrist are suitable for bone age assessment because the hand and wrist possess many bones and taking radiographs of the hand and wrist is easy. The original TW2 method was developed using radiographs of average ...

    The Bayley and Pinneau (BP) method is most commonly used for height prediction. The height prediction tables were developed by Bayley and Pinneau in 1950 and revised in 1959. They have been established according to the bone age assessment standards of Greulich and Plye. The tables can be used for children from the age of 6 years and become more acc...

    The Khamis-Roche Method predicts adult stature, without determining the bone age. It uses age, gender, child height and weight, mother height, and father height. This method is valid for children above the age of 4. Although the Khamis-Roche method is considered an accurate predictor, it is not as accurate as methods using the bone age.

    CDC Growth Chart; Boys: 2 to 20 years; Stature-for-age and Weight-for-age percentiles Pediatric growth charts from the Centers for Disease Control and Prevention (CDC) have been used over decades by pediatricians, nurses, and parents in the US to track the growth of infants, children, and adolescents. The growth charts consist of percentile curves ...

    Online height calculators try to predict the adult height of children and adolescents by simply entering personal data. These height calculators can give you an educated guess about the adult height, but the previously described methods lead to more accurate results.

    The most accurate methods to predict the adult height of children and adolescents are certainly the methods based on the bone age. Although those methods are scientifically investigated, they should be used with caution. Natural variations in growth development and environmental factors are not taken into account. Several factors can negatively aff...

  4. Introduction. These instructions are for BoneXpert Online, a browser-based application for bone age assessment. The application is intended for interactive use. For clinical use, the application interprets images in DICOM format. The JPG, PNG, and BMP file formats are also supported for research purposes.

  5. Oct 25, 2011 · The recently developed automated BoneXpert method improves the Bayley–Pinneau method by modelling the growth potential (the fraction of adult height left to grow) as a non-linear function of two variables, bone age and bone age delay.

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  7. The starting point is the BayleyPinneau method which predicts the fraction of adult height achieved from the bone age. Children with advanced bone age (early maturers) tend to have a stronger growth spurt, and late maturers have a weaker growth spurt.

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