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  1. Nov 1, 2023 · Exclusion criteria were: i) animal studies; ii) studies with subjects without a precise anxiety disorder diagnosis or with anxiety as specifier and not primarily diagnosed; iii) performing non-pharmacological comparators; iv) performing nutraceuticals, complementary and alternative medicine (e.g., acupuncture, meditation, yoga, hypnotherapy, traditional herbal medicine); v) contemplating any ...

  2. Sep 30, 2014 · Azapirones are a class of drugs used as anxiolytics. They are associated with less drowsiness, psychomotor impairment, alcohol potentiation and potential for addiction or abuse than benzodiazepines. However, azapirones are not widely used in the treatment of panic disorder and evidence for their efficacy is unclear.

    • 10.1002/14651858.CD010828.pub2
    • 2014/09
  3. Jul 31, 2017 · 1987 to present 1 Panic Attack/ or Panic/ or Panic Disorder/ 2 Agoraphobia/ 3 (panic or agoraphobi*).mp. 4 adnos.ti,ab,id. 5 (anxiety disorder* adj2 otherwise specified).ti,ab,id. 6 or/1‐5 7 exp Antidepressant Drugs/ 8 Neurotransmitter Uptake Inhibitors/ or exp serotonin norepinephrine reuptake inhibitors/ or exp serotonin reuptake inhibitors/ 9 exp Monoamine Oxidase Inhibitors/ 10 exp ...

  4. Generalized anxiety disorder is one of the most common anxiety disorders and can be costly if unrecognized or left untreated. Azapirones are a group of drugs that work at the 5-HT1A receptor and are used to treat patients suffering from GAD. This systematic review evaluates the effectiveness of azapirones compared to other treatments.

  5. Nov 1, 2023 · The present SR and meta-analysis is the first to assess azapirones’ efficacy for anxiety disorders. Compared to the most current meta-analyses on the matter (Chessick et al., 2006; Imai et al., 2014), the present report not only accounts for anxiety disorders other than GAD and PD but also provides an up-to-date evaluation of azapirones in such disorders, different outcomes, and GRADE ...

  6. Aug 4, 2023 · It is often associated with other psychiatric disorders, such as drug dependence, major depression, bipolar disorder, social phobia, specific phobia and generalised anxiety disorder. Azapirones ...

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  8. The focus of research on the pharmacotherapy of anxiety disorders has shifted from serotonin, norepinephrine and GABA systems to other neurotransmitters and pathways including glutamate and neuropeptides (89). Presented below is a review of recent and ongoing studies of medications for GAD, PD, and SAD.

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