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  1. Nov 1, 2023 · Exclusion criteria were: i) animal studies; ii) studies with subjects without a precise anxiety disorder diagnosis or with anxiety as specifier and not primarily diagnosed; iii) performing non-pharmacological comparators; iv) performing nutraceuticals, complementary and alternative medicine (e.g., acupuncture, meditation, yoga, hypnotherapy, traditional herbal medicine); v) contemplating any ...

  2. Sep 30, 2014 · Azapirones are a class of drugs used as anxiolytics. They are associated with less drowsiness, psychomotor impairment, alcohol potentiation and potential for addiction or abuse than benzodiazepines. However, azapirones are not widely used in the treatment of panic disorder and evidence for their efficacy is unclear.

    • 10.1002/14651858.CD010828.pub2
    • 2014/09
  3. Jul 31, 2017 · A panic attack is a discrete period of fear or anxiety that has a rapid onset, reaches a peak within 10 minutes and in which at least 4 of 13 characteristic symptoms are experienced. Many of these symptoms involve bodily systems, such as racing heart, chest pain, sweating, shaking, dizziness, flushing, churning stomach, faintness and ...

  4. Generalized anxiety disorder is one of the most common anxiety disorders and can be costly if unrecognized or left untreated. Azapirones are a group of drugs that work at the 5-HT1A receptor and are used to treat patients suffering from GAD. This systematic review evaluates the effectiveness of azapirones compared to other treatments.

  5. Symptoms of generalised anxiety disorder (GAD) The main symptom of generalised anxiety disorder (GAD) is feelings of stress or worry that affect your daily life and are difficult to control. Other symptoms of GAD may include: difficulty sleeping. feeling restless, irritable or finding it difficult to concentrate. getting tired easily.

  6. Nov 1, 2023 · The present SR and meta-analysis is the first to assess azapirones’ efficacy for anxiety disorders. Compared to the most current meta-analyses on the matter (Chessick et al., 2006; Imai et al., 2014), the present report not only accounts for anxiety disorders other than GAD and PD but also provides an up-to-date evaluation of azapirones in such disorders, different outcomes, and GRADE ...

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  8. A small amount of moderate-quality evidence suggested that the acceptability of azapirones for panic disorder was lower than for placebo. However, only trials of one azapirone (namely buspirone) were included in this review; this, combined with the small sample size, limits our conclusions. If further research is to be conducted, studies with ...

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