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1. www.nhs.uk › medicines › adalimumabSide effects of adalimumab - NHS

   www.nhs.uk › medicines › adalimumab

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   Common side effects. These common side effects of adalimumab happen in more than 1 in 10 people. There are things you can do to help cope with them: Pain, swelling, redness or itchy skin where your injection was given. Mild nose, throat or sinus infection.

2. www.ncbi.nlm.nih.gov › pmc › articlesDrug-Induced Liver Injury Caused by Adalimumab: A Case Report ...

   www.ncbi.nlm.nih.gov › pmc › articles

   May 14, 2013 · We report a case of adalimumab-induced cholestasis (pruritus, increase of cholestatic enzymes with elevated AST and ALT) in a patient with RA and chronic hepatitis C infection. Drug-induced liver injury (DILI) is one of the most common ADRs and the main cause of drugs withdrawal.

   • Author: Bernardo Frider, Andres Bruno, Marcelo Ponte, Marcelo Amante
   • DOI: 10.1155/2013/406901

   • Publish Year: 2013
   • Publication: Case Reports Hepatol. 2013; 2013: 406901.

3. bnf.nice.org.uk › drugs › adalimumabAdalimumab | Drugs | BNF | NICE

   bnf.nice.org.uk › drugs › adalimumab

   View adalimumab information, including dose, uses, side-effects, pregnancy, breast feeding, contra-indications and monitoring requirements.

4. www.ncbi.nlm.nih.gov › pmc › articlesHepatotoxicity Associated with the Use of Anti-TNF-α Agents

   www.ncbi.nlm.nih.gov › pmc › articles

   Despite the growing evidence of this relationship, the pathogenesis of this reaction remains incompletely understood, but it appears to depend on characteristics of the medications and the genetic composition of the patients; it is likely more complicated than a simple medication class effect.

   • Author: Joshua B. French, Maurizio Bonacini, Marwan Ghabril, David Foureau, Herbert L. Bonkovsky, Herbert L....
   • DOI: 10.1007/s40264-015-0366-9

   • Publish Year: 2016
   • Published: 2016/03

5. www.journal-of-hepatology.eu › article › S0168-8278Infliximab-induced liver injury: Clinical phenotypes ...

   www.journal-of-hepatology.eu › article › S0168-8278

   Infliximab has been associated with drug-induced liver injury (DILI), particularly drug-induced autoimmune hepatitis (DIAIH). DIAIH is commonly treated with corticosteroids, but there is limited data on the efficacy of corticosteroids in infliximab-induced DILI.

   • Author: Helgi Kristinn Björnsson, Helgi Kristinn Björnsson, Bjorn Gudbjornsson, Einar Stefan Björnsson

   • Publish Year: 2021

6. www.ncbi.nlm.nih.gov › pmc › articlesInfliximab-induced autoimmune hepatitis - PMC

   www.ncbi.nlm.nih.gov › pmc › articles

   May 24, 2021 · Anti-tumour necrosis factor alpha (TNFα) drugs are one of the more commonly implicated medications in immune-mediated liver injury and recent literature suggests a substantial association with drug-induced AIH and this particular class of drugs.

7. People also ask

   Does adalimumab have hepatotoxicity?

   • The prescribing information for adalimumab, etanercept, golimumab and certolizumab lists “hepatotoxicity” or “elevated liver enzymes” in the “Postmarketing Experience” and/or “Adverse Reactions” sections [ 13 – 17 ].

   Hepatotoxicity Associated with the Use of Anti-TNF-α Agents

   www.ncbi.nlm.nih.gov/pmc/articles/PMC4752395/

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   Does infliximab cause autoimmune hepatitis (Dili)?

   • Overall 75% of patients were switched to another biologic agent; no DILI due to the second biologic was observed. Infliximab has been associated with drug-induced liver injury (DILI), particularly drug-induced autoimmune hepatitis (DIAIH).

   Infliximab-induced liver injury: Clinical ... - Journal of Hepatology

   www.journal-of-hepatology.eu/article/S0168-8278(21)02022-5/fulltext

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   What are the side effects of adalimumab?

   • Serious side effects are uncommon and affect less than 1 in 100 people. Tell your doctor or call 111 now if: In rare cases, adalimumab may cause a serious allergic reaction (anaphylaxis). You or the person who's unwell may also have a rash that's swollen, raised, itchy, blistered or peeling.

   Side effects of adalimumab - NHS

   www.nhs.uk/medicines/adalimumab/side-effects-of-adalimumab/

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   Can adalimumab cause a rash?

   • Tell your doctor or call 111 now if: In rare cases, adalimumab may cause a serious allergic reaction (anaphylaxis). You or the person who's unwell may also have a rash that's swollen, raised, itchy, blistered or peeling. These can be signs of a serious allergic reaction and may need immediate treatment in hospital.

   Side effects of adalimumab - NHS

   www.nhs.uk/medicines/adalimumab/side-effects-of-adalimumab/

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   What happens if I stop taking adalimumab?

   • You might get side effects up to 4 months after you stop taking adalimumab. Speak to your doctor if you get any side effects. Serious side effects are uncommon and affect less than 1 in 100 people. Tell your doctor or call 111 now if: In rare cases, adalimumab may cause a serious allergic reaction (anaphylaxis).

   Side effects of adalimumab - NHS

   www.nhs.uk/medicines/adalimumab/side-effects-of-adalimumab/

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   How long does adalimumab take to normalize liver enzymes?

   • Time from peak ALT to normalization of liver enzymes was 45 days in the corticosteroid group vs. 77 days in others ( p = 0.062). Corticosteroids were tapered in all patients, with no cases of relapse during the follow-up period of 1,245 (820-2,698) days. Overall 75% received another biologic, mostly adalimumab, without evidence of liver injury.

   Infliximab-induced liver injury: Clinical ... - Journal of Hepatology

   www.journal-of-hepatology.eu/article/S0168-8278(21)02022-5/fulltext

   See all results for this question

8. www.bsg.org.uk › web-education › drug-induced-liverDrug-induced Liver Injury - BSG

   www.bsg.org.uk › web-education › drug-induced-liver

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   Histological characteristics of checkpoint-inhibitor-liver injury are different from DILI of other drugs and AIH and include granulomas and central endotheliitis (caused by anti-CTL A-4 therapy) or lobular hepatitis (caused by anti- PD-1 or anti P.D.- L1 therapy) (4).