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  1. The medical dictum primum non nocere (first, do no harm) is usually attributed to Hippocrates, and a poignant modern example of the injunction’s warning lies in the balance between the legitimate value and inappropriate use of the substances derived from the opium poppy plant.

    • National Academy of Medicine
    • 2017
  2. Apr 5, 2024 · The number of opioid-related deaths has been rising continuously since 1999. Three distinct waves of increases are related to different types of opioids throughout the last 25 years. Increasing communities' support, capacity, and education may help turn the tide and prevent overdose deaths.

  3. Dec 26, 2021 · Today: why we should replace the punitive approach of the "war on drugs" with a radical new paradigm for treating addiction. In 1986, Maia Szalavitz was addicted to heroin in New York City ...

    • do no harm: the opioid epidemic meaning of life will1
    • do no harm: the opioid epidemic meaning of life will2
    • do no harm: the opioid epidemic meaning of life will3
    • do no harm: the opioid epidemic meaning of life will4
    • do no harm: the opioid epidemic meaning of life will5
    • Key Facts
    • Opioids
    • Opioid Overdose
    • Risk Factors For Opioid Overdose
    • Emergency Responses to Opioid Overdose
    • People Most Likely to Witness An Opioid Overdose
    • Prevention of Opioid Overdose
    • Who Response and Recommendations
    The term “opioids” includes compounds that are extracted from the poppy plant (Papaver somniferum)as well as semisynthetic and synthetic compounds with similar properties that can interact with opi...
    Opioids are commonly used for the treatment of pain, and include medicines such as morphine, fentanyl and tramadol.
    Their non-medical use, prolonged use, misuse and use without medical supervision can lead to opioid dependence and other health problems.
    Due to their pharmacological effects, opioids can cause breathing difficulties, and opioid overdose can lead to death.

    The term “opioids” includes compounds that are extracted from the poppy plant (Papaver somniferum) as well as semisynthetic and synthetic compounds with similar properties that can interact with opioid receptors in the brain. Opioids have analgesic and sedative effects, and such medicines as morphine, codeine and fentanyl are commonly used for the ...

    Opioid use can lead to death due to the effects of opioids on the part of the brain which regulates breathing. An opioid overdose can be identified by a combination of three signs and symptoms: 1. pinpoint pupils 2. unconsciousness 3. difficulties with breathing. Worldwide, about 600 000 deaths were attributable to drug use in 2019. Close to 80% of...

    There are a number of risk factors for opioid overdose. These include: 1. having an opioid use disorder; 2. taking opioids by injection; 3. resumption of opioid use after an extended period of abstinence (e.g. following detoxification, release from incarceration, cessation of treatment); 4. using prescription opioids without medical supervision; 5....

    Death following opioid overdose is preventable if the person receives basic life support and the timely administration of the drug naloxone. Naloxone is an antidote to opioids that will reverse the effects of an opioid overdose if administered in time. Naloxone has virtually no effect in people who have not taken opioids. Access to naloxone is gene...

    People who are most likely to witness an opioid overdose are: 1. people at risk of an opioid overdose themselves; 2. friends and families of people who use opioids on a regular basis; and 3. health-care workers, the emergency services, people providing accommodation to people who use opioids, and peer education and outreach workers as well as other...

    Beyond approaches to reducing drug use in general in the community, there are specific measures to prevent opioid overdose. These include: 1. increasing the availability of opioid dependence treatment, including for those dependent on prescription opioids; 2. reducing and preventing irrational or inappropriate opioid prescribing; 3. monitoring opio...

    WHO supports countries in their efforts to ensure rational use of opioids and their optimal availability for medical purposes and minimization of their misuse and non-medical use. Following the recommendation of WHO’s Expert Committee on Drug Dependence (6), a number of synthetic opioids, including fentanyl analogues, have been placed under interna...

  4. what is the magnitude of the opioid epidemic? which opioids are most commonly involved in overdose deaths? what are the associated characteristics of those with opioid use disorder? how does the opioid epidemic impact our families and our communities? what has driven the epidemic?

  5. The opioid epidemic now afflicts 2.5 million Americans, kills more than 90 every day, disrupts the lives of tens of millions more in the circles of victims’ concerned families and loved ones, and imposes overwhelming treatment, financial, and organizational burdens on our states, communities, health care organizations, and clinicians.

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  7. The medical dictum primum non nocere (first, do no harm) is usually attributed to Hippocrates, and a poignant modern example of the injunction’s warning lies in the balance between the legitimate value and inappropriate use of the substances derived from the opium poppy plant.

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