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  1. Jun 13, 2013 · In this article, we discuss the current views on the renal regulation of acid-base metabolism and the diagnostic approach to children with metabolic acidosis, including the major characteristics of the different types of renal tubular acidosis (RTA), focusing on distal RTA (dRTA).

  2. Dec 2, 2021 · In children, renal tubular acidosis (RTA) is due to either an inherited or acquired defect that affects the kidney's ability to absorb filtered bicarbonate, or excrete ammonia or titratable acid. RTA is characterized by a normal anion gap (hyperchloremic) metabolic acidosis caused by the net retention of hydrogen or loss of bicarbonate.

  3. Renal tubular acidosis (RTA) This term is applied to a group of transport defect in the reabsorption of bicarbonate, excretion of hydrogen ions or both. The RTA syndromes are characterized by a relatively normal GFR, hyperchloraemic metabolic acidosis with normal serum anion gap. The hyperchloraemia is a

  4. Renal tubular acidosis (RTA) is a common inherited tubulopathy in children. Proximal RTA, usually secondary to a systemic metabolic disease, is characterized by a generalized dysfunction of the proximal tubule resulting in Fanconi syndrome.

    • Soumya Reddy, Nivedita Kamath
    • 2021
  5. Karl S. Roth, MD*†. Objectives After completing this article, readers should be able to: Describe the important presenting characteristics of renal tubular acidosis (RTA). Delineate the mechanisms of the growth failure commonly encountered in RTA. Characterize the various types of primary RTA.

    • 394KB
    • 11
  6. Three subtypes of RTA are recognized. Type I or distal RTA: the classic form. Type II or proximal RTA: the bicarbonate-wasting form. Type III, or hyperkalemic RTA (rare in children): associated with hyporeninemic hypoaldosteronism or inherited in an autosomal manner.

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  8. The term renal tubular acidosis (RTA) describes a group of uncommon kidney disorders characterized by defective acid-base regulation. Reaching the diagnosis of RTA is complex and often delayed, resulting in suboptimal treatment. Methods:

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