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Oct 30, 2023 · Bone formation in a developing embryo begins in mesenchyme and occurs through one of two processes: either endochondral or intramembranous osteogenesis (ossification). Intramembranous ossification is characterized by the formation of bone tissue directly from mesenchyme.
- Julie Doll
- Content Manager
Sep 25, 2024 · In a long bone, for example, at about 6 to 8 weeks after conception, some of the mesenchymal cells differentiate into chondrocytes (cartilage cells) that form the cartilaginous skeletal precursor of the bones (Figure \(\PageIndex{2.1}\)).
Describe the microscopic and gross anatomical structures of bones. Identify the gross anatomical features of a bone. Describe the histology of bone tissue, including the function of bone cells and matrix. Compare and contrast compact and spongy bone. Identify the structures that compose compact and spongy bone.
- Lindsay M. Biga, Sierra Dawson, Amy Harwell, Robin Hopkins, Joel Kaufmann, Mike LeMaster, Philip Mat...
- 2019
- Cartilage Templates
- Intermembranous Ossification
- Endochondral Ossification
- How Bones Grow in Length
- How Bones Growth in Diameter
- Bone Remodelling
- Diseases of The Skeletal System
Bone is a replacement tissue; that is, it uses a model tissue on which to lay down its mineral matrix. For skeletal development, the most common template is cartilage. During foetal development, a framework is laid down that determines where bones will form. This framework is a flexible, semi-solid matrix produced by chondroblasts and consists of h...
During intramembranous ossification, compact and spongy bone develops directly from sheets of mesenchymal (undifferentiated) connective tissue. The flat bones of the face, most of the cranial bones, and the clavicles (collarbones) are formed via intramembranous ossification. The process begins when mesenchymal cells in the embryonic skeleton gather...
In endochondral ossification, bone develops by replacinghyaline cartilage. Cartilage does not become bone. Instead, cartilage serves as a template to be completely replaced by new bone. Endochondral ossification takes much longer than intramembranous ossification. Bones at the base of the skull and long bones form via endochondral ossification. In ...
The epiphyseal plate is the area of growth in a long bone. It is a layer of hyaline cartilage where ossification occurs in immature bones. On the epiphyseal side of the epiphyseal plate, cartilage is formed. On the diaphyseal side, cartilage is ossified, and the diaphysis grows in length. The epiphyseal plate is composed of four zones of cells and ...
While bones are increasing in length, they are also increasing in diameter; growth in diameter can continue even after longitudinal growth ceases. This is called appositional growth. Osteoclasts resorb old bone that lines the medullary cavity, while osteoblasts, via intramembranous ossification, produce new bone tissue beneath the periosteum. The e...
The process in which matrix is resorbed on one surface of a bone and deposited on another is known as bone modelling. Modelling primarily takes place during a bone’s growth. However, in adult life, bone undergoes remodelling, in which resorption of old or damaged bone takes place on the same surface where osteoblasts lay new bone to replace that wh...
Osteogenesis imperfecta (OI) is a genetic disease in which bones do not form properly and therefore are fragile and break easily. It is also called brittle bone disease. The disease is present from birth and affects a person throughout life. The genetic mutation that causes OI affects the body’s production of collagen, one of the critical component...
- Anna Chruścik, Kate Kauter, Louisa Windus, Eliza Whiteside
- 2021
Sep 27, 2024 · Skeletal system photos and labeled diagrams can help you to understand the parts of the skeleton, how it's organized, the conditions that can affect it, and tests used to diagnose skeletal health. The skeletal system comprises 206 bones and has two main parts: the axial skeleton and the appendicular skeleton.
Oct 30, 2023 · Bones make up the skeletal system of the human body. The adult human has two hundred and six bones. There are several types of bones that are grouped together due to their general features, such as shape, placement and additional properties.
Oct 23, 2022 · In the areas of the skeleton where bones move (for example, the ribcage and joints), cartilage, a semi-rigid form of connective tissue, provides flexibility and smooth surfaces for movement. The skeletal system is the body system composed of bones and cartilage.
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