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Nature

A comprehensive comparison of tools for fitting mutational signatures - Nature Communications

COSMICv3 contains 67 mutational signatures (18 are artifact signatures) defined in 96 mutational contexts. While newer COSMIC versions (the latest version is 3.4 from October ...

2 days ago

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How will the Budget impact the prime housing market?

3 days ago

Nature

Engineering immunogens that select for specific mutations in HIV broadly neutralizing antibodies - Nature Communications

In this work, researchers engineer HIV-1 immunogens using molecular dynamics simulations to enhance vaccine designs that select for specific antibody mutations. Their approach improved the selection ...

20 hours ago

Nature

Single-cell transcriptomics of rectal organoids from individuals with perianal fistulizing Crohn’s disease reveals patient-specific signatures - Scientific Reports

Perianal fistulizing Crohn’s disease (CD) is a severe gastrointestinal disorder causing extensive mucosal damage with limited treatment options. Severe manifestations of the disease appear at ...

5 days ago

Nature

Stochastic properties of musical time series - Nature Communications

For ease of access and readability, we based our study on musical pieces stored in MIDI (“.mid”) format. It is commonly used in music production, performance and analysis. MIDI files are therefore ...

7 days ago

Nature

Teleportation with embezzling catalysts - Communications Physics

Quantum teleportation offers superior performance in transmitting information over classical methods but is often hindered by environmental noise. To address this issue, the authors introduce ...

5 days ago