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- inflammation, a response triggered by damage to living tissues.
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Definition and cause of inflammation. Inflammation occurs in response to injury resulting from infection, foreign substances, or other causes, including antigen-antibody (Ag-Ab) complexes. Inflammation is necessary for alleviating and repairing injury; however, excessive inflammation can be damaging to host tissues.
Define inflammation. What is the purpose of inflammation? What are some possible causes of inflammation? Vascular and cellular defensive immune response that delivers fluid, substances and cells from the blood to interstitial fluid and to the area of the infection/injury.
- Overview
- Causes
- Signs
- Vascular changes
•Redness is caused by the dilation of small blood vessels in the area of injury.
•Heat results from increased blood flow through the area and is experienced only in peripheral parts of the body such as the skin. Fever is brought about by chemical mediators of inflammation and contributes to the rise in temperature at the injury.
•Swelling, called edema, is caused primarily by the accumulation of fluid outside the blood vessels.
•The pain associated with inflammation results in part from the distortion of tissues caused by edema, and it also is induced by certain chemical mediators of inflammation, such as bradykinin, serotonin, and the prostaglandins.
The factors that can stimulate inflammation include microorganisms, physical agents, chemicals, inappropriate immunological responses, and tissue death. Infectious agents such as viruses and bacteria are some of the most common stimuli of inflammation. Viruses give rise to inflammation by entering and destroying cells of the body; bacteria release ...
The four cardinal signs of inflammation—redness (Latin rubor), heat (calor), swelling (tumor), and pain (dolor)—were described in the 1st century ad by the Roman medical writer Aulus Cornelius Celsus. Redness is caused by the dilation of small blood vessels in the area of injury. Heat results from increased blood flow through the area and is experienced only in peripheral parts of the body such as the skin. Fever is brought about by chemical mediators of inflammation and contributes to the rise in temperature at the injury. Swelling, called edema, is caused primarily by the accumulation of fluid outside the blood vessels. The pain associated with inflammation results in part from the distortion of tissues caused by edema, and it also is induced by certain chemical mediators of inflammation, such as bradykinin, serotonin, and the prostaglandins.
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Diseases, Disorders, and More: A Medical Quiz
A fifth consequence of inflammation is the loss of function of the inflamed area, a feature noted by German pathologist Rudolf Virchow in the 19th century. Loss of function may result from pain that inhibits mobility or from severe swelling that prevents movement in the area.
When tissue is first injured, the small blood vessels in the damaged area constrict momentarily, a process called vasoconstriction. Following this transient event, which is believed to be of little importance to the inflammatory response, the blood vessels dilate (vasodilation), increasing blood flow into the area. Vasodilation may last from 15 minutes to several hours.
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Next, the walls of the blood vessels, which normally allow only water and salts to pass through easily, become more permeable. Protein-rich fluid, called exudate, is now able to exit into the tissues. Substances in the exudate include clotting factors, which help prevent the spread of infectious agents throughout the body. Other proteins include antibodies that help destroy invading microorganisms.
- The Editors of Encyclopaedia Britannica
Dec 31, 2020 · Inflammation is a response of a tissue to injury, often injury caused by invading pathogens. It is characterized by increased blood flow to the tissue causing increased temperature, redness, swelling, and pain.
Inflammation is a natural response that our body has to injury or infection. It helps protect us from potential harm and promotes healing. Inflammation involves blood vessels dilating and becoming more permeable, and attracting more immune cells and fluid into local tissue.
Apr 9, 2024 · Inflammation, also known as the inflammatory response, is a biological reaction initiated by the immune system, particularly in vascular tissues, as a defense mechanism against harmful stimuli. These stimuli can range from microorganisms to foreign substances that pose a threat to the body.
