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      • : a local response to cellular injury that is marked by capillary dilatation, leukocytic infiltration, redness, heat, pain, swelling, and often loss of function and that serves as a mechanism initiating the elimination of noxious agents and of damaged tissue
      www.merriam-webster.com/dictionary/inflammation
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  2. Inflammation is the body’s normal physiological response to injury. The cause of tissue injury is attributed to trauma, autoimmune, microbial, heat and toxins (chemicals). When tissue injury occurs, numerous substances are released by the injured tissues, which cause changes to the surrounding uninjured tissues.

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  3. Jul 27, 2012 · From five cardinal signs, there is actually just one specific macroscopic sign of inflammation, namely localized edema. Further, the driving force for tissue fluid accumulation is defined in biochemical terms and as such taken for the definition of the inflammatory process.

  4. Aug 1, 2011 · Inflammation is an essential response provided by the immune systems that ensures the survival during infection and tissue injury. Inflammatory responses are essential for the maintenance of...

  5. Oct 18, 2022 · With the benefit of insights from molecular biology that were unavailable before the 1960s, it is possible to define inflammation more broadly as a protective response, involving the activation of immune and non-immune cells, in response to an insult such as infection, toxic compounds, damaged cells, or irradiation, with the aim to restore ...

  6. Inflammation may be defined as a degenerative process which is intense enough to cause local accumulation of low molecular weight catabolic products, which in turn elevates tissue osmotic pressure that attracts extra fluid, with or without heat release sufficient for significant elevation of tissue temperature.

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  7. Inflammation is essential to stave off infection and for coordinating various aspects of the repair and regeneration process; however, when it is misregulated or becomes chronic, it can cause severe tissue damage.

  8. Sep 27, 2023 · Inflammation can be defined as either a localized or systemic response of the body to external (e.g., trauma) or internal (e.g., ischemia, infection) triggers. Physiologically, inflammation restores the affected tissue to its preinjury state. The phases of the inflammatory response can be classified as either acute or chronic. The acute phase ...