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  1. Nov 23, 2019 · Bone marrow lesions (BMLs) are localized areas of edema within subchondral bone, which are often due to early chondromalacia changes, subchondral insufficiency stress or microfractures, and/or avascular necrosis. The presence of BMLs worsen outcomes after arthroscopy and arthroplasty, thus making their management important in the preservation of hip function. In recent years, the advent of ...

    • Nikhil Kapil, Linsen T. Samuel, Atul F. Kamath
    • 2020
  2. Introduction. Osteonecrosis (ON) of the femoral head is a progressive disease commonly seen in patients aged younger than 40 years. 1-3 The disease is a multifatorial process characterized by an insult to the blood supply, leading to trabecular and subchondral bone death, ultimately progressing to fracture and collapse of the joint surface. 4-9 Treatments for the disease process are based on ...

  3. A bone marrow biopsy can help doctors: • detect any abnormal cells in the bone marrow. • identify and diagnose the cause of any abnormal blood cell counts. • decide on the best treatment for some blood conditions. • monitor the progression of certain conditions. • assess how treatment is working.

  4. Dec 7, 2020 · Abstract. Bone marrow lesions (BML) are painful changes in subchondral bone which can be reliably identified on magnetic resonance imaging and have been identified in patients suffering from hip osteoarthritis (OA) and related conditions. Created via repetitive microdamage at the articular surface and dysregulated subchondral healing, BML have ...

    • Maria A Munsch, Marc R Safran, Matthew C Mai, W Kelton Vasileff
    • 10.1093/jhps/hnaa056
    • 2021
    • J Hip Preserv Surg. 2020 Aug; 7(3): 401-409.
  5. Bone marrow aspirate (BMA) intra-articular injection is a minimally invasive orthobiologic treatment option for osteoarthritis (OA). Hip OA affects a significant portion of the population and has a paucity of data surrounding orthobiologic treatments. The primary objective of this study was to delineate the clinical impact of bone marrow ...

  6. Bone marrow transplant. Bone marrow is soft tissue that lives in the cavities of some bones and is the source of all blood cells. If you have a bone marrow transplant (BMT) at Great Ormond Street Hospital (GOSH) it replaces cells in bone marrow and swaps them for new cells. These might be your own cells, or cells from a related or unrelated donor.

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  8. Aug 15, 2021 · Biologically augmented surgical treatments of orthopaedic conditions are increasingly popular. Bone marrow aspirate concentrate is a key orthobiologic tissue source, and the field is moving from the standard iliac crest marrow aspiration toward local aspirations of marrow depots that are accessible during the standard-of-care procedures in an attempt to reduce morbidity, surgery time, and cost.

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