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  1. The opioid epidemic, also referred to as the opioid crisis, is the rapid increase in the overuse, misuse/abuse, and overdose deaths attributed either in part or in whole to the class of drugs called opiates/opioids since the 1990s. It includes the significant medical, social, psychological, demographic and economic consequences of the medical ...

  2. Apr 5, 2024 · Opioid-involved death rates decreased by 12.5%. Prescription opioid-involved death rates remained the same. Heroin-involved death rates decreased nearly 36%. Synthetic opioid-involved death rates (excluding methadone) increased over 4%. 1.

    • Key Facts
    • Opioids
    • Opioid Overdose
    • Risk Factors For Opioid Overdose
    • Emergency Responses to Opioid Overdose
    • People Most Likely to Witness An Opioid Overdose
    • Prevention of Opioid Overdose
    • Who Response and Recommendations
    The term “opioids” includes compounds that are extracted from the poppy plant (Papaver somniferum)as well as semisynthetic and synthetic compounds with similar properties that can interact with opi...
    Opioids are commonly used for the treatment of pain, and include medicines such as morphine, fentanyl and tramadol.
    Their non-medical use, prolonged use, misuse and use without medical supervision can lead to opioid dependence and other health problems.
    Due to their pharmacological effects, opioids can cause breathing difficulties, and opioid overdose can lead to death.

    The term “opioids” includes compounds that are extracted from the poppy plant (Papaver somniferum) as well as semisynthetic and synthetic compounds with similar properties that can interact with opioid receptors in the brain. Opioids have analgesic and sedative effects, and such medicines as morphine, codeine and fentanyl are commonly used for the ...

    Opioid use can lead to death due to the effects of opioids on the part of the brain which regulates breathing. An opioid overdose can be identified by a combination of three signs and symptoms: 1. pinpoint pupils 2. unconsciousness 3. difficulties with breathing. Worldwide, about 600 000 deaths were attributable to drug use in 2019. Close to 80% of...

    There are a number of risk factors for opioid overdose. These include: 1. having an opioid use disorder; 2. taking opioids by injection; 3. resumption of opioid use after an extended period of abstinence (e.g. following detoxification, release from incarceration, cessation of treatment); 4. using prescription opioids without medical supervision; 5....

    Death following opioid overdose is preventable if the person receives basic life support and the timely administration of the drug naloxone. Naloxone is an antidote to opioids that will reverse the effects of an opioid overdose if administered in time. Naloxone has virtually no effect in people who have not taken opioids. Access to naloxone is gene...

    People who are most likely to witness an opioid overdose are: 1. people at risk of an opioid overdose themselves; 2. friends and families of people who use opioids on a regular basis; and 3. health-care workers, the emergency services, people providing accommodation to people who use opioids, and peer education and outreach workers as well as other...

    Beyond approaches to reducing drug use in general in the community, there are specific measures to prevent opioid overdose. These include: 1. increasing the availability of opioid dependence treatment, including for those dependent on prescription opioids; 2. reducing and preventing irrational or inappropriate opioid prescribing; 3. monitoring opio...

    WHO supports countries in their efforts to ensure rational use of opioids and their optimal availability for medical purposes and minimization of their misuse and non-medical use. Following the recommendation of WHO’s Expert Committee on Drug Dependence (6), a number of synthetic opioids, including fentanyl analogues, have been placed under interna...

  3. Nov 15, 2021 · Although cardiologists are typically not considered avid opioid prescribers, the current report highlights that the opioid epidemic affects all medical and surgical disciplines, and that everyone has an equal responsibility if we are to end the opioid epidemic.

    • Enas S Kandil
    • 2021
  4. For that reason, heroin is associated with a much more severe withdrawal than a drug such as buprenorphine, which clears the brain more slowly. Opioids drugs with longer half-lives, slower clearance rates and slower brain uptake are favored for the treatment of OUD.

    • Nora D. Volkow, Carlos Blanco
    • 10.1038/s41380-020-0661-4
    • 2021
    • 2021/01
  5. And unknown at the time, these new populations of persons with addiction to prescription-type opioid were primed for even greater dependence and crisis from the coming influx of heroin and illicit fentanyl in subsequent years.

  6. How has the COVID-19 pandemic affected the opioid crisis? The COVID-19 pandemic in the U.S. isn’t just about COVID-19, it’s about managing all of the spillover effects, including the effects it has had on people with addiction and substance use disorder.

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