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  1. Feb 9, 2011 · Biochemical systems biology augments more traditional disciplines, such as genomics, biochemistry and molecular biology, by championing (i) mathematical and computational modeling; (ii) the application of traditional engineering practices in the analysis of biochemical systems; and in the past decade increasingly (iii) the use of near ...

    • Vladimir A Likic, Malcolm J McConville, Trevor J Lithgow, Antony Bacic, Antony Bacic
    • 10.1155/2010/268925
    • 2010
    • Adv Bioinformatics. 2010; 2010: 268925.
  2. According to the interpretation of systems biology as using large data sets using interdisciplinary tools, a typical application is metabolomics, which is the complete set of all the metabolic products, metabolites, in the system at the organism, cell, or tissue level.

  3. Nov 10, 2010 · Here, we review the state of the field with a focus on four emerging applications of systems biology that are likely to be of particular importance during the decade to follow: (a) pathway-based biomarkers, (b) global genetic interaction maps, (c) systems approaches to identify disease genes, and (d) stem cell systems biology. We also cover ...

    • Han-Yu Chuang, Matan Hofree, Trey Ideker
    • 10.1146/annurev-cellbio-100109-104122
    • 2010
    • 2010/11/11
  4. Systems Biology is one of the new and fast developing fields in science. This book is the first to give a comprehensive definition and overview, and to highlight the applications of systems biology. Includes supplementary material: sn.pub/extras.

  5. The most feasible application of systems biology research is to create a detailed model of cell regulation, focused on particular signal-transduction cascades and molecules to provide system-level insights into mechanism-based drug discovery (26–28).

    • Hiroaki Kitano
    • 2002
  6. Jul 7, 2017 · Here, we summarize the elements of engineering science that have shaped our view of systems biology and its application to fundamental knowledge, bioremediation, and human health.

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  8. May 20, 2010 · Systems biology is an experimental science, and many definitions of systems biology include repeated iterations between modeling, prediction and experimentation at their core. However, this seems unsatisfactory if the prediction remains restricted to “local” perturbations of existing systems.

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