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- Agglutination is a biological process in which particles, such as cells or microorganisms, clump together in the presence of specific antibodies. This phenomenon occurs when antibodies bind to antigens present on the surface of these particles, causing them to stick together and form visible aggregates or clumps.
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Oct 7, 2024 · These reactions involve the clumping of particles and can be used to detect antibodies or antigens, making them indispensable tools for disease diagnosis and blood typing. Understanding how agglutination works and its different types helps enhance diagnostic accuracy and efficacy in clinical settings.
Feb 28, 2023 · The purpose of agglutination is to detect the presence of specific antigens or antibodies in samples of bodily fluids, such as blood, saliva, urine, or cerebrospinal fluid (CSF); as well as to identify specific strains of bacteria in microbiological cultures.
Jul 30, 2023 · Definition of Agglutination: Agglutination is the process of particles clumping together due to specific interactions between antigens and antibodies. Types of Agglutination: There are several types of agglutination, each with its own specific context and applications. Here are some common types:
Nov 14, 2023 · Agglutination can be used as an indicator of the presence of antibodies against bacteria or red blood cells. Agglutination assays are usually quick and easy to perform on a glass slide or microtiter plate (Figure 50.6.3.1 50.6.3. 1).
Apr 10, 2024 · Definition of Agglutination Reaction. Agglutination reaction is a specific antigen-antibody reaction where visible clumping of particles occurs when a particulate antigen combines with its corresponding antibody under specific conditions of temperature, pH, and electrolyte presence.
Agglutination occurs when an insoluble or particle antigen interacts with an antibody. A positive reaction can be detected macroscopically in a short time. However, the antigen-antibody complex may be seen with the naked eye if the complex size is large. Both IgG or IgM could be involved in the agglutination reaction.
Learning Objectives. Compare direct and indirect agglutination. Identify various uses of hemagglutination in the diagnosis of disease. Explain how blood types are determined. Explain the steps used to cross-match blood to be used in a transfusion.