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Jan 1, 2014 · The agglutination phenomena can be defined as the linkage of particles or cells in a liquid resulting in formation of clumps. In detail, aggregation/agglutination is the outcome of...
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Agglutination is clumping together in suspension of cells bearing the antigen (epitopes)/ antigen bearing microorganisms, or particles in the presence of specific antibodies called “agglutinins”.
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A ring precipitation test is used for grouping streptococci and for determining unknown proteins.
Single-diffusion assays, which are also called immunodiffusion assays, can be used to determine the concentration of immunoglobulins, complement components, and other serum proteins.
This test is used to diagnose several fungal, viral and bacterial infections. In addi-tion, it can be used to diagnose autoimmune diseases and to recognize Corynebacterium diphtheriae-produced toxins.
The agglutination test is used widely, for example, in detecting streptococci group B toxins, rheumatoid arthritis, and C-reactive proteins.
Blood grouping, virus identification and in the detection of certain diseases.
In the ring precipitation test, antigen interaction with antibodies occurs at: The top layer of the reaction tube. (b) The middle layer of the reaction tube. The bottom layer of the reaction tube. (d) None of the above. 2. Gel diffusion can be: Single. (b) Double. (c) Ring. (d) a and b. In the direct agglutination test: Pathogen and patient antibod...
Nov 3, 2023 · Agglutination is the visible expression of the aggregation of antigens and antibodies. Agglutination reactions apply to particulate test antigens that have been conjugated to a carrier. The carrier could be artificial (such as latex or charcoal particles) or biological (such as red blood cells).
When multiple antibodies bind to multiple antigens on diferent pathogens, it leads to agglutination. This clumping makes it easier for immune cells to engulf and eliminate the pathogens, thus enhancing the body's defense against infection. In microbiology, agglutination can occur in various ways.
Apr 10, 2024 · Definition of Agglutination Reaction. Agglutination reaction is a specific antigen-antibody reaction where visible clumping of particles occurs when a particulate antigen combines with its corresponding antibody under specific conditions of temperature, pH, and electrolyte presence.
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Apr 21, 2024 · Antibodies can agglutinate cells or large particles into a visible matrix. Agglutination tests are often done on cards or in microtiter plates that allow multiple reactions to take place side by side using small volumes of reagents.