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Agglutination is one of the antigen and specific antibody reactions in-vitro in laboratory in the presence of electrolytes at a suitable temperature and pH. Agglutination is used for diagnosis of diseases in laboratory either uses the particulate or soluble antigens. Agglutination involves two steps.
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Jan 1, 2014 · The agglutination phenomena can be defined as the linkage of particles or cells in a liquid resulting in formation of clumps. In detail, aggregation/agglutination is the outcome of connections...
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A ring precipitation test is used for grouping streptococci and for determining unknown proteins.
Single-diffusion assays, which are also called immunodiffusion assays, can be used to determine the concentration of immunoglobulins, complement components, and other serum proteins.
This test is used to diagnose several fungal, viral and bacterial infections. In addi-tion, it can be used to diagnose autoimmune diseases and to recognize Corynebacterium diphtheriae-produced toxins.
The agglutination test is used widely, for example, in detecting streptococci group B toxins, rheumatoid arthritis, and C-reactive proteins.
Blood grouping, virus identification and in the detection of certain diseases.
In the ring precipitation test, antigen interaction with antibodies occurs at: The top layer of the reaction tube. (b) The middle layer of the reaction tube. The bottom layer of the reaction tube. (d) None of the above. 2. Gel diffusion can be: Single. (b) Double. (c) Ring. (d) a and b. In the direct agglutination test: Pathogen and patient antibod...
Agglutination, the process of particle clumping or aggregation, plays a pivotal role in both biological and medical realms. This article explores the concept of agglutination, elucidating its mechanisms and diverse applications.
Learning Objectives. Compare direct and indirect agglutination. Identify various uses of hemagglutination in the diagnosis of disease. Explain how blood types are determined. Explain the steps used to cross-match blood to be used in a transfusion.
May 24, 2018 · Direct Agglutination. In the direct agglutination test, the pathogen itself is used to detect specific antibodies against that pathogen [2]. The reaction between the patient-specific antibodies in the sera and the surface of the pathogen leads to the formation of visible clumps (agglutination) [2].
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Understanding Agglutination: A Crucial Process in Biology and ...