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Daniela MERLO, Laboratory Head | Cited by 2,399 | of Istituto Superiore di Sanità, Rome (ISS) | Read 65 publications | Contact Daniela MERLO
May 25, 2016 · This special issue includes four reviews and four original research articles focusing on the physiological and pathological role of DNA damage and repair mechanisms, synaptic plasticity, and neurodegeneration. Moreover, the emerging roles played in memory and neurodegeneration by different factors involved in the stress response, chromatin ...
- Daniela Merlo, Inmaculada Cuchillo-Ibañez, Rosanna Parlato, Gerhard Rammes
- 2016
PhD - Cited by 2,940 - Neurobiologia
Mar 5, 2021 · In addition, the direct conversion of patient-specific cells could be used to implement disease-relevant in vitro platforms to generate models for neurodegenerative diseases, identify targets, and screen potential therapeutic drugs.
- Cristiana Mollinari, Daniela Merlo
- 10.1007/s11064-021-03282-5
- 2021
- Neurochem Res. 2021; 46(6): 1330-1336.
Daniela Merlo 1 , Inmaculada Cuchillo-Ibañez 2 , Rosanna Parlato 3 , Gerhard Rammes 4 Affiliations 1 Department of Cell Biology and Neuroscience, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
- Daniela Merlo, Inmaculada Cuchillo-Ibañez, Rosanna Parlato, Gerhard Rammes
- 2016
Jan 31, 2016 · The main DNA repair pathways, nucleotide excision repair (NER), base excision repair (BER), mismatch repair (MMR), homologous recombination (HR), and nonhomologous end-joining (NHEJ), are devoted to the repair of specific DNA alterations and complementary in some respects.
In this Commentary we present and discuss strength and weakness of several strategies for the direct cellular reprogramming from somatic cells to generate human brain cells which maintain age-related features.
