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  1. Nov 10, 2021 · We conducted the Prospective ARNI versus ACE Inhibitor Trial to Determine Superiority in Reducing Heart Failure Events after Myocardial Infarction (PARADISE-MI), an international, multicenter ...

    • Marc A. Pfeffer, Brian Claggett, Eldrin F. Lewis, Christopher B. Granger, Lars Køber, Aldo P. Maggio...
    • 2021
  2. Jun 26, 2019 · ARNI improved functional capacity in patients with heart failure (HF) and a reduced ejection fraction (EF), including increasing New York Heart Association functional class (MD −0.79, 95% CI −0.86, −0.71) and 6‐minute walking distance (MD 27.62 m, 95% CI 15.76, 39.48).

    • Yiwen Wang, Ran Zhou, Chi Lu, Qing Chen, Tongda Xu, Dongye Li
    • 2019
  3. Angiotensin Receptor–Neprilysin Inhibition (ARNI) Therapy and Reverse Remodeling in Heart Failure With Reduced Ejection Fraction. Mark H. Drazner, MD, MSc 1. Author Affiliations Article Information. 1 Division of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas.

    • Mark H. Drazner
    • 2019
  4. Mar 8, 2024 · Contemporary use of sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) and angiotensin receptor‐neprilysin inhibitors (ARNi) in patients with atrial fibrillation (AF) and heart failure (HF) has not been described.

  5. Apr 17, 2023 · ARNI has demonstrated superior cardioprotective effects compared with renin–angiotensin system inhibitors (RAS‐Is) in large clinical trials such as the PARADIGM‐HF (Prospective Comparison of ARNI With ACEI [Angiotensin‐Converting Enzyme Inhibitor] to Determine Impact on Global Mortality and Morbidity in Heart Failure) trial.

  6. May 2, 2022 · This review focuses on the potential utilization of angiotensin receptor–neprilysin inhibitors (ARNIs) to manage conditions in the continuum from hypertension to heart failure based on...

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  8. Jul 21, 2021 · Angiotensin receptor-neprilysin inhibitors (ARNIs) are a new class of cardiovascular agents characterized by their dual action on the major regulators of the cardiovascular system,...

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