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    • Corticobasal degeneration

      • Corticobasal degeneration, also called corticobasal syndrome, is a rare disease that causes areas of the brain to shrink. Over time, nerve cells break down and die. Corticobasal degeneration affects the area of the brain that processes information and brain structures that control movement.
      www.mayoclinic.org/diseases-conditions/corticobasal-degeneration/symptoms-causes/syc-20354767
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  2. Dec 22, 2023 · Corticobasal degeneration, also called corticobasal syndrome, is a rare disease that causes areas of the brain to shrink. Over time, nerve cells break down and die. Corticobasal degeneration affects the area of the brain that processes information and brain structures that control movement.

  3. Dec 22, 2023 · A diagnosis of corticobasal degeneration (corticobasal syndrome) is made based on your symptoms, exam and testing. However, your symptoms could be due to another disease that affects the brain. Conditions that cause similar symptoms include progressive supranuclear palsy, Alzheimer's disease, Pick's disease or Creutzfeldt-Jakob disease.

  4. Dec 22, 2023 · Mayo Clinic experts have extensive experience in diagnosing and treating people with corticobasal degeneration (corticobasal syndrome) and other neurological conditions. Corticobasal syndrome is estimated to occur in about two out of 100,000 people.

  5. Corticobasal degeneration (CBD) is a rare condition that can cause gradually worsening problems with movement, speech, memory and swallowing. It's often also called corticobasal syndrome (CBS). CBD is caused by increasing numbers of brain cells becoming damaged or dying over time.

  6. Sep 15, 2022 · CBS is a rare neurodegenerative disorder that gradually worsens your physical and cognitive functions. The buildup of a toxic protein in your brain cells called tau causes CBS.

  7. Jan 1, 2013 · Probable CBD criteria require insidious onset and gradual progression for at least 1 year, age at onset ≥50 years, no similar family history or known tau mutations, and a clinical phenotype of probable CBS or either FBS or naPPA with at least 1 CBS feature.

  8. Corticobasal syndrome (CBS) is one of the clinical phenotypes associated with CBD pathology, manifesting as a progressive asymmetric akinetic-rigid, poorly levodopa-responsive parkinsonism, with cerebral cortical dysfunction.

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