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1. www.ncbi.nlm.nih.gov › pmc › articlesAngiotensin Receptor-Neprilysin Inhibitor (ARNI) and Cardiac ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Aug 20, 2021 · This review summarizes the possible link between ARNI and cardiac arrhythmias and discusses potential underlying mechanisms, providing novel insights about the therapeutic role and safety profile of ARNI in the cardiovascular system.

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     Sudden cardiac deaths (SCD) and all-cause mortality:...

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     The renin-angiotensin-aldosterone system (RAAS) plays a...

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     Indeed, a new class of drug, the angiotensin...

2. www.ncbi.nlm.nih.gov › pmc › articlesPractical Recommendations for the Use of Angiotensin Receptor ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Jun 29, 2023 · The use of ARNI in heart failure is supported by clinical trials and guidelines, with ARNI being one of the four medications recommended for treating heart failure with reduced ejection fraction (HFrEF).

   • DOI: 10.1007/s40119-023-00323-8
   • Published: 2023/09

   • Publication: Cardiol Ther. 2023 Sep; 12(3): 445-471.

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4. www.nature.com › articles › s41440/021/00706-1Angiotensin receptor-neprilysin inhibitors: Comprehensive ...

   www.nature.com › articles › s41440/021/00706-1

   Jul 21, 2021 · The apparent clinical benefit of one ARNI, sacubitril/valsartan, as shown in clinical trials, has positioned the drug class as a first-line therapy in patients with heart failure, particularly...

   • Author: Koichi Yamamoto, Hiromi Rakugi

   • Publish Year: 2021

5. www.ncbi.nlm.nih.gov › pmc › articlesARNi: A Novel Approach to Counteract Cardiovascular Diseases

   www.ncbi.nlm.nih.gov › pmc › articles

   Apr 28, 2019 · Indeed, a new class of drug, the angiotensin receptor–neprilysin inhibitors (ARNi), has the ability to counteract the effects of angiotensin II as well as to increase the activity of NPs. ARNi have already been proven to be effective in the treatment of heart failure with reduced ejection fraction.

   • Author: Massimo Volpe, Speranza Rubattu, Allegra Battistoni

   • Publish Year: 2019

6. www.jacc.org › doi › 10From ACE Inhibitors/ARBs to ARNIs in Coronary Artery Disease ...

   www.jacc.org › doi › 10

   Although there is convincing evidence to support the role of renin-angiotensin system (RAS) blockade for the treatment of HFrEF, there is a lack of evidence to indicate that RAS inhibition is an effective strategy for heart failure with preserved ejection fraction (HFpEF).

   • Author: Darryl P. Leong, Darryl P. Leong, John J.V. McMurray, Philip G. Joseph, Salim Yusuf

   • Publish Year: 2019

7. www.nature.com › articles › nrcardioLong-term neprilysin inhibition — implications for ARNIs

   www.nature.com › articles › nrcardio

   Dec 15, 2016 · The dual-acting angiotensin-receptor–neprilysin inhibitor (ARNI) LCZ696, approved for treatment of heart failure with reduced ejection fraction, is the first approval for chronic neprilysin...

8. People also ask

   Can an Arni treat hypertension clinically?

   • To decide whether to apply an ARNI to treat hypertension clinically, it is important to understand the potential properties of the drug in modulating multiple factors inside and outside the cardiovascular system beyond its effect on reducing peripheral blood pressure.

   Angiotensin receptor-neprilysin inhibitors: Comprehensive review a…

   www.nature.com/articles/s41440-021-00706-1

   See all results for this question

   Can Arni be used in heart failure?

   • The use of ARNI in heart failure is supported by clinical trials and guidelines, with ARNI being one of the four medications recommended for treating heart failure with reduced ejection fraction (HFrEF). ARNIs can improve diastolic and left ventricular function, quality of life, and reduce the risk of ventricular arrhythmias.

   Practical Recommendations for the Use of Angiotensin Receptor

   www.ncbi.nlm.nih.gov/pmc/articles/PMC10423183/

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   Can Arni be used to treat heart failure with reduced ejection fraction?

   • ARNi have already been proven to be effective in the treatment of heart failure with reduced ejection fraction. New evidence has suggested that, in the next years, the field of ARNi application will widen to include other CVDs, such as heart failure, with preserved ejection fraction and hypertension.

   ARNi: A Novel Approach to Counteract Cardiovascular Diseases

   www.ncbi.nlm.nih.gov/pmc/articles/PMC6539682/

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   Does Arni reduce ventricular arrhythmias?

   • Moreover, the paper highlights the role of ARNI in heart failure management, with numerous clinical trials that have demonstrated its effectiveness in reducing cardiovascular death or heart failure hospitalization, enhancing quality of life, and diminishing the risk of ventricular arrhythmias.

   Practical Recommendations for the Use of Angiotensin Receptor

   www.ncbi.nlm.nih.gov/pmc/articles/PMC10423183/

   See all results for this question

   What are Arni angiotensin receptor–neprilysin inhibitors (Arni)?

   • ARNI angiotensin receptor–neprilysin inhibitors (ARNI), HTN hypertension, HFrEF heart failure with reduced ejection fraction, DM diabetes mellitus, IHD ischemic heart disease, GDMT guideline-directed medical therapy

   Practical Recommendations for the Use of Angiotensin Receptor

   www.ncbi.nlm.nih.gov/pmc/articles/PMC10423183/

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   Can Arni improve peritoneal dialysis patients' heart failure symptoms?

   • Twenty-one HFpEF patients on peritoneal dialysis patients from a Chinese study with ARNI was found to have a tendency to enhance cardiac function and to considerably improve heart failure symptoms and signs as well as the levels of heart failure markers .

   Practical Recommendations for the Use of Angiotensin Receptor

   www.ncbi.nlm.nih.gov/pmc/articles/PMC10423183/

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9. pubmed.ncbi.nlm.nih.gov › 34290389Angiotensin receptor-neprilysin inhibitors: Comprehensive ...

   pubmed.ncbi.nlm.nih.gov › 34290389

   To decide whether to apply an ARNI to treat hypertension clinically, it is important to understand the potential properties of the drug in modulating multiple factors inside and outside the cardiovascular system beyond its effect on reducing peripheral blood pressure.