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Arthur Kornberg (March 3, 1918 – October 26, 2007) was an American biochemist who won the Nobel Prize in Physiology or Medicine 1959 for the discovery of "the mechanisms in the biological synthesis of ribonucleic acid and deoxyribonucleic acid " together with Spanish biochemist and physician Severo Ochoa of New York University.
Arthur Kornberg, who had founded the department, had discovered DNA polymerase, together with his then–postdoctoral fellow, Bob Lehman (also on the Stanford biochemistry faculty), and had won...
Kornberg turned instead to some of the smallest bacterial viruses (phages), such as the phi X174 and M13 viruses of E. coli, for his study. With their comparatively short DNA strands, these viruses are easier to keep intact during handling, and their biological activity is easy to observe.
The Nobel Prize in Physiology or Medicine 1959 was awarded jointly to Severo Ochoa and Arthur Kornberg "for their discovery of the mechanisms in the biological synthesis of ribonucleic acid and deoxyribonucleic acid"
Dec 5, 2007 · Arthur Kornberg was one of the greatest biochemists of the twentieth century. His career spanned more than 60 years, and such has been the impact of his work on modern biomedical science that...
- Tania A. Baker
- 2007
Nov 16, 2007 · Beginning with his experience in Ochoa's lab, and for the rest of his life, Arthur committed to the principle that any complex cellular process from nucleotide metabolism to chromosome replication can and must be examined with pure enzymes and substrates.
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Dec 9, 2005 · In the first Classic, Kornberg and his colleagues describe the purification of DNA polymerase from E. coli. In the second Classic, they report that polymerized DNA, Mg 2+, and all four deoxynucleoside triphosphates (adenine, guanine, cytosine, and thymine) are needed for DNA synthesis to occur.
