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  1. Feb 22, 2024 · Sacroiliitis (say-kroe-il-e-I-tis) is a painful condition that affects one or both sacroiliac joints. These joints sit where the lower spine and pelvis meet. Sacroiliitis can cause pain and stiffness in the buttocks or lower back, and the pain might go down one or both legs.

  2. Apr 1, 2015 · A substantial body of neuropathic pain research points to several important contributory mechanisms including aberrant ectopic activity in nociceptive nerves, peripheral and central sensitization, impaired inhibitory modulation, and pathological activation of microglia.

    • Ian Gilron, Ralf Baron, Troels Jensen
    • 2015
  3. Thus, in comparing neuropathic pain in children vs adults, one can expect substantial differences in prevalence, presenting symptoms, course of disease or pain, especially with regard to chronicity, duration, and recurrences, and potential effect of different treatments.

    • Gary A. Walco, Robert H. Dworkin, Elliot J. Krane, Alyssa A. LeBel, Rolf Detlef Treede
    • 2010
  4. May 10, 2022 · Overview. Complex regional pain syndrome (CRPS) is a form of chronic pain that usually affects an arm or a leg. complex regional pain syndrome (CRPS) typically develops after an injury, a surgery, a stroke or a heart attack. The pain is out of proportion to the severity of the initial injury.

  5. Mar 1, 2016 · Patients with a possible central pain syndrome should be examined to determine whether there is impaired pinprick and/or temperature sensation (indicating spinothalamic tract dysfunction) in the neurologically affected painful limb.

    • James C. Watson, Paola Sandroni
    • 2016
  6. Apr 1, 2023 · Many patients with central sensitization say that a hug or a pat on the back hurts them, clothing irritates their skin, or a heavy blanket exerts painful pressure. Global sensory hyperresponsiveness, in which the patient is extremely affected by external and internal stimuli.

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  8. Sep 11, 2018 · Adolescents in this study discussed how chronic pain was “arresting” their developmental progression. But beyond a sense of interruption of pain on development is a sense of pain “stealing” their identity, the very nature of the individual they are.

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