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1. www.acc.org › latest-in-cardiology › journal-scansComparative Effectiveness of ACE Inhibitors and ARBs

   www.acc.org › latest-in-cardiology › journal-scans

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   Aug 3, 2021 · Abnormal weight loss was more common and abnormal weight gain less common with ACE inhibitors compared to ARBs. Perspective: This study evaluated real-world outcome of patients with newly treated HTN initiating treatment with either an ACE inhibitor or ARB.

2. www.ahajournals.org › doi › 10Comparative First-Line Effectiveness and Safety of ACE ...

   www.ahajournals.org › doi › 10

   Jul 26, 2021 · In our large-scale, observational network study, ARBs do not differ statistically significantly in effectiveness at the class level compared with ACE inhibitors as first-line treatment for hypertension but present a better safety profile.

   • Author: RuiJun Chen, Marc A Suchard, Harlan M Krumholz, Martijn J Schuemie, Martijn J Schuemie, Steven Shea,...

   • Publish Year: 2021

3. pubmed.ncbi.nlm.nih.gov › 36443599Real-world comparative effectiveness of ARNI versus ACEi/ARB ...

   pubmed.ncbi.nlm.nih.gov › 36443599

   We assessed the real-world effectiveness of ARNI versus angiotensin-converting enzyme inhibitor/angiotensin receptor blocker (ACEi/ARB) on all-cause and cardiovascular (CV)-related mortality and hospitalizations in heart failure (HF) with reduced or mildly reduced ejection fraction (EF).

4. www.everydayhealth.com › heart-failure › consumersWhat to Know About ARNIs for Heart Failure - Everyday Health

   www.everydayhealth.com › heart-failure › consumers

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   Feb 15, 2023 · 1. There is one ARNI that has been approved by the FDA to treat heart failure. Sacubitril/valsartan, sold under the brand name Entresto, is the first and only ARNI drug approved so far by the...

5. www.jacc.org › doi › 10From ACE Inhibitors/ARBs to ARNIs in Coronary Artery Disease ...

   www.jacc.org › doi › 10

   ARB is an acceptable alternative when ACE inhibitor is not tolerated (principally due to cough), and MRA should be added to the ACE inhibitor/ARB. ARNI represents a new and more effective alternative to ACE inhibitor for patients with HFrEF.

   • Author: Darryl P. Leong, Darryl P. Leong, John J.V. McMurray, Philip G. Joseph, Salim Yusuf

   • Publish Year: 2019

6. www.nejm.org › doi › fullAngiotensin Receptor–Neprilysin Inhibition in Acute ...

   www.nejm.org › doi › full

   Nov 10, 2021 · We conducted the Prospective ARNI versus ACE Inhibitor Trial to Determine Superiority in Reducing Heart Failure Events after Myocardial Infarction (PARADISE-MI), an international, multicenter...

7. People also ask

   Are Arni drugs better than ACE inhibitors?

   • Compared to ACE inhibitors or ARBs, ARNI drugs can: Help you live longer. Improve your quality of life. Slow down your heart failure progression. Reduce the amount of time you spend in a hospital. Every year, about 60,000 people die from heart failure.

   ARNI to Treat Heart Failure - Cleveland Clinic

   my.clevelandclinic.org/health/treatments/23939-angiotensin-receptor-neprilysin-inhibitor-arni

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   Are ACE inhibitors better than ARBs?

   • Abnormal weight loss was more common and abnormal weight gain less common with ACE inhibitors compared to ARBs. This study evaluated real-world outcome of patients with newly treated HTN initiating treatment with either an ACE inhibitor or ARB. The authors suggest the study supports starting ARBs over ACE inhibitors.

   Comparative Effectiveness of ACE Inhibitors and ARBs

   www.acc.org/latest-in-cardiology/journal-scans/2021/08/03/19/47/comparative-effectiveness-of-ace-inhibitors-and-arbs

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   Can I take an Arni drug if I have heart failure?

   • You can take an ARNI drug if you just got a diagnosis of heart failure with a reduced ejection fraction (a measure of your heart’s pumping function) of 40% or less. A normal ejection fraction is 55% to 65%. Also, you can switch to an ARNI drug if you were taking an ACE inhibitor or ARB for heart failure.

   ARNI to Treat Heart Failure - Cleveland Clinic

   my.clevelandclinic.org/health/treatments/23939-angiotensin-receptor-neprilysin-inhibitor-arni

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   Who should not take Arni drugs?

   • You shouldn’t take ARNI drugs if you: Got angioedema (facial swelling) when you took an ACE inhibitor or ARB drug. Are pregnant or nursing. Are still taking an ACE inhibitor or ARB drug. Have a serious liver problem. Are taking aliskiren. Are overly sensitive to ARBs or ARNIs.

   ARNI to Treat Heart Failure - Cleveland Clinic

   my.clevelandclinic.org/health/treatments/23939-angiotensin-receptor-neprilysin-inhibitor-arni

   See all results for this question

   Is Arni better than ACE inhibitor for HFrEF?

   • The beneficial effects of ARNI over ACE inhibitor were consistent among participants with and without an implantable cardioverter-defibrillator, among those taking and not taking a MRA, and among those taking higher and lower doses of beta-blocker (44), suggesting that ARNI are efficacious even in patients who are treated optimally for HFrEF.

   From ACE Inhibitors/ARBs to ARNIs in Coronary Artery Disease and Heart

   www.jacc.org/doi/10.1016/j.jacc.2019.04.068

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   Which Arni is best for heart failure?

   • 1. There is one ARNI that has been approved by the FDA to treat heart failure. Sacubitril/valsartan, sold under the brand name Entresto, is the first and only ARNI drug approved so far by the FDA to treat people with heart failure. 2. ARNIs can treat both diastolic and systolic heart failure.

   What to Know About ARNIs for Heart Failure - Everyday Health

   www.everydayhealth.com/heart-failure/consumers-guide-to-angiotensin-receptor-neprilysin-inhibitors-for-heart-failure/

   See all results for this question

8. my.clevelandclinic.org › health › treatmentsARNI to Treat Heart Failure - Cleveland Clinic

   my.clevelandclinic.org › health › treatments

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   Jul 29, 2022 · ARNI medication could prevent more than 28,000 deaths a year if providers prescribed it to more people instead of ACE inhibitors or ARBs. A large study found that participants taking an ARNI drug had a 20% drop in their risk of cardiovascular death or hospitalization for heart failure.