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Apr 24, 2023 · The skin appendages are epidermal and dermal-derived components of the skin that include hair, nails, sweat glands, and sebaceous glands. Each component has a unique structure, function, and histology. This article describes the unique characteristics of each of these components and provides insight into tissue preparation for microscopic evaluation and the clinical significance of these ...
- Hani Yousef, Julia H. Miao, Mandy Alhajj, Talel Badri
- 2023/04/24
- 2020
Skin Appendages. Skin appendages include nails, hair, sebaceous glands, eccrine (sweat) glands, and apocrine glands. They have two distinct components: superficial and deeper components in the dermis, which are down growths of epidermis. Dermal component regulates differentiation of the appendage.
Skin Appendage Tumors. Most tumors of skin appendages (hair shafts, sweat glands, and apocrine glands) have characteristic morphologic features that mimic their cell of origin (e.g., hair shaft, eccrine gland). The vast majority of these tumors behave in a benign (or at most locally aggressive) fashion, and metastasis is exceptionally rare.
The skin covers the entire body and is the largest organ of the body. It covers a surface area of more than 1.7 m2, making up in total about 16% of normal body weight. 1 It has an array of functions. These include acting as a barrier to physical, biological and chemical agents, as well as to ultraviolet (UV) radiation.
- 4 Histological Structure of Human Skin
- Stratum Corneum
- 4.2.2 Dermal Layer
- 4.2.3 Dermal Cell
Histologically, skin consists of three layers including epider-mis, dermis, and hypodermis.
Stratum corneum is the outermost dead layer of the skin, made up from attened nonnucleated cells called“squames fl ” (Fig. 6). These cells overlap at their lateral margins and interlock with cells of apposed layers by ridges, grooves, and microvilli. In thin skin, this layer may be only a few cell layers in depth, but in thick skin, it may be const...
The dermis is formed from two layers of connective tissue including the upper one, so-called papillary layer, and the lower one, so-called reticular layer.
The dermis contains many various cells with its own function such as broblasts, mast cells, different immune cells, fi smooth muscle cells, and specialized muscle cells.
Jul 31, 2023 · The skin contains several glands, hair, nails and nerve endings that allow it to function optimally. This article will discuss the embryology, gross anatomical and histological features of the appendages of the skin. Additionally, pathologies that affect the appendages and their consequences will also be discussed.
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Apr 24, 2023 · The skin appendages are epidermal and dermal-derived components of the skin that include hair, nails, sweat glands, and sebaceous glands. Each component has a unique structure, function, and histology. This article describes the unique characteristics of each of these components and provides insight into tissue preparation for microscopic ...
