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Apr 24, 2023 · The skin appendages are epidermal and dermal-derived components of the skin that include hair, nails, sweat glands, and sebaceous glands. Each component has a unique structure, function, and histology. This article describes the unique characteristics of each of these components and provides insight into tissue preparation for microscopic evaluation and the clinical significance of these ...
- Hani Yousef, Julia H. Miao, Mandy Alhajj, Talel Badri
- 2023/04/24
- 2020
Feb 1, 2015 · The three types are: Skin problems affected by stress or other emotional states. Psychological problems caused by disfiguring skin disorders. Psychiatric disorders that manifest themselves via the skin, such as delusional parasitosis. "Psychologists' service provision skills are highly applicable and relevant," she says.
Jul 23, 2023 · Explore the histology of skin appendages and their functions in thermoregulation, protection, sensory perception, and aesthetics. Learn about the clinical significance of skin appendage histology in diagnosis, treatment, and cosmetic interventions. Deepen your knowledge of skin appendage histology for comprehensive skin understanding.
Skin appendages play important roles in various functions, including protection, sensation, thermoregulation, and excretion. The distribution and characteristics of skin appendages vary across different regions of the body. Abnormalities or diseases affecting skin appendages can lead to various dermatological conditions.
- Skin Condition
- Skin Hydration and Occlusion
- Skin Age
- Site-To-Site Variation
- Race
- Skin Temperature
- Vehicle Effects
Skin barrier and skin permeability normally relates to the ingress of chemicals into and across intact, healthy skin, and the determination of skin “quality” is significant in experiments which determine percutaneous absorption (see Chap. 2). This infers that models of skin permeation are therefore models of permeation across intact skin and do not...
An increase in skin hydration is widely associated with an increase in the rate of penetration of most molecules. The exact nature and magnitude of such changes have been attributed to the physicochemical nature of the penetrant and the specific mechanism by which excess hydration is induced. Imokawa et al. (1991) suggested that the stratum corneum...
The structure and appearance of skin changes significantly with age, but it is often unclear if such changes are as a result of inherent ageing or influenced by environmental factors, or a combination of both. At the lower extreme of age, the infant (usually under two years of age) has, compared to adult skin, a higher water content and the stratum...
Wide variations in absorption rates have been found across different skin sites in the same individual and between different individuals. The permeability rates of molecules can generally be related to the thickness of the skin at particular points on the body. Wester and Maibach (1999) reported that this regional variation in absorption did not re...
The issue of whether race influence affects percutaneous absorption is complicated by the paucity of studies in this area. Of the few studies carried out, Lotte et al. (1993) suggested that there are no substantial differences between the permeability of African, Asian or European skin. They further suggested that greater skin pigmentation presents...
It is generally accepted that an increase in temperature will increase the rate of absorption and that a decrease in temperature may lower the rate of absorption by up to one order of magnitude (Fritsch and Stoughton 1963; van der Merwe et al. 1988; Woolfson and McCafferty 1993a, b). An increase in temperature will also affect blood flow and metabo...
As discussed above, percutaneous penetration is a series of diffusion and partition steps from, and between, a number of compartments. These rates rely on the collective effects that the skin, penetrant and vehicle exert on the diffusion process. In pharmaceutical applications, the vehicle allows optimisation and control of release at a rate adequa...
- Gary P. Moss, Darren R. Gullick, Simon C. Wilkinson
- 2015
The skin covers the entire body and is the largest organ of the body. It covers a surface area of more than 1.7 m2, making up in total about 16% of normal body weight. 1 It has an array of functions. These include acting as a barrier to physical, biological and chemical agents, as well as to ultraviolet (UV) radiation.
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Skin appendages (or adnexa of skin) are anatomical skin-associated structures that serve a particular function including sensation, contractility, lubrication and heat loss in animals. In humans, some of the more common skin appendages are hairs (sensation, heat loss, filter for breathing, protection), arrector pilli (smooth muscles that pull ...
