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  1. Apr 24, 2023 · The skin appendages are epidermal and dermal-derived components of the skin that include hair, nails, sweat glands, and sebaceous glands. Each component has a unique structure, function, and histology. This article describes the unique characteristics of each of these components and provides insight into tissue preparation for microscopic evaluation and the clinical significance of these ...

    • Hani Yousef, Julia H. Miao, Mandy Alhajj, Talel Badri
    • 2023/04/24
    • 2020
  2. Jul 31, 2023 · The skin contains several glands, hair, nails and nerve endings that allow it to function optimally. This article will discuss the embryology, gross anatomical and histological features of the appendages of the skin. Additionally, pathologies that affect the appendages and their consequences will also be discussed.

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    • Epidermis
    • Dermis
    • Hypodermis

    The epidermis is the most superficial layer of the skin, and is largely formed by layers of keratinocytes undergoing terminal maturation. This involves increased keratin production and migration toward the external surface, a process termed cornification. There are also several non-keratinocytecells that inhabit the epidermis: 1. Melanocytes – resp...

    The dermis is immediately deep to the epidermis and is tightly connected to it through a highly-corrugated dermo-epidermal junction. The dermis has only two layers, which are less clearly defined than the layers of the epidermis. They are the superficial papillary layer, and the deeper reticular layer. The reticular layer is considerably thicker, a...

    The hypodermis, or subcutaneous tissue, is immediately deep to the dermis. It is a major body store of adipose tissue, and as such can vary in size between individuals depending on the amount of fatty tissue present.

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  3. Skin appendages develop from the epidermis and dermis during embryonic development. Skin appendages play important roles in various functions, including protection, sensation, thermoregulation, and excretion. The distribution and characteristics of skin appendages vary across different regions of the body.

  4. Jul 31, 2023 · This article will describe the anatomy and histology of the skin. Undoubtedly, the skin is the largest organ in the human body; literally covering you from head to toe. The organ constitutes almost 8-20% of body mass and has a surface area of approximately 1.6 to 1.8 m2, in an adult. It is comprised of three major layers: epidermis, dermis and ...

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  5. Aug 21, 2023 · mesoderm. , is the innermost layer of the skin and is mainly composed of fat and connective tissue. Skin appendages are derived from the skin and include hair, nails, and glands. The main functions of the skin are protection (barrier against ultraviolet radiation, microorganisms, and water loss), the synthesis of. vitamin D.

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  7. May 1, 2023 · Skin is part of the integumentary system and considered to be the largest organ of the human body. There are three main layers of skin: the epidermis, the dermis, and the hypodermis (subcutaneous fat). The focus of this topic is on the epidermal and dermal layers of skin. Skin appendages such as sweat glands, hair follicles, and sebaceous glands are reviewed in-depth elsewhere.[1]

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