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In this installment of the‘Antibodies to watch ’ article series, we review the antibody therapeutics that were approved in the EU or US in 2017, and provide details of those that, as of December 1, 2017, were being reviewed by either the European Medicines Agency (EMA) or the US Food and Drug Adminis-tration (FDA).
Mar 26, 2021 · A total of six different anti-SARS-CoV-2 antibody kits, including one LFIA RDT kits using gold conjugate (SD Biosensor Inc., Suwon, Korea, detecting IgM and IgG antibodies against nucleocapsid protein (NCP)), two FIA kits using europium particles (SD Biosensor Inc., detecting IgM and IgG antibodies against NCP; and Boditech Med Inc., Chuncheon ...
- Jae Hoon Ko, Eun Jeong Joo, Jin Yang Baek, Kyungmin Huh, Sun Young Cho, Cheol In Kang, Doo Ryeon Chu...
- 2021
Oct 23, 2024 · New research shows that, in a head-to-head comparison of five tests used to detect COVID-19 antibodies (known as ‘immunoassays’), an assay manufactured by Siemens and one developed by an academic partnership led by the University of Oxford had the most accurate results.
This review focuses briefly on types, molecular targets, mechanism of actions and therapeutic indications of FDA approved MAb products that are currently available in the market.
- Surjit Singh, Nitish Kumar, Pradeep Dwiwedi, Jaykaran Charan, Rimplejeet Kaur, Preeti Sidhu, Vinay K...
- 2017
The role of autoantibodies in the investigation and management of patients with diabetes. The measurement of these antibodies in patients with diabetes is part of many research projects and it is clear that the presence of these antibodies does confer an increased risk of developing type I diabetes.
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Jan 5, 2022 · Antinuclear antibody (ANA) testing dates back over 70 years (1) and is one of the few surviving immunoassays from the 1960s and 1970 era. Although the conceptual use of indirect immunofluorescence assays (IFA) at the core of ANA testing has remained relatively unchanged, the technical aspects and microscopy components (i.e., optics, light ...
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A wide range of in vitro tests with multiple formats of different complexity can be utilized to characterize i) the antibody-binding domains of the mAb, such as on-target binding and downstream pharmacological effects (e.g. immunosuppression, immune activation, cytokine release) in both humans and animal species used for toxicology studies and o...
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