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Apr 12, 2023 · ALT levels such as 60, 70, 80, 90, or 100 U/L are frequently discovered accidentally during routine laboratory investigations. In addition, mild elevations of ALT are often asymptomatic. The two most common causes of mildly elevated ALT are nonalcoholic fatty liver diseases (NAFLD) and medications.
May 1, 2024 · Normal blood ALT and AST levels range from 0 to 40 IU/L. Abnormal results. Marked elevations of ALT or AST (greater than 1,000 IU/L) suggest drug-induced liver injury (such as paracetamol overdose), acute viral hepatitis, ischaemic, or autoimmune hepatitis and may require referral to secondary care for further follow up. ALP
Mar 24, 2018 · The pattern of ALT to ALP rise can indicate whether the pathology is primarily cholestatic or hepatocellular: A greater than 10-fold increase in ALT and a less than 3-fold increase in ALP suggests a predominantly hepatocellular injury
Jul 1, 2017 · In adults, the American College of Gastroenterology (ACG) recommends ALT URLs of 33 U/L for males and 25 U/L for females, respectively, and that individuals with enzyme catalytic activity concentrations above these URLs should be further investigated (1).
Levels of ALT and AST are usually high in conditions such as hepatitis – possibly twenty to fifty times higher than normal. The ALT ‘value’, or level, is more specific to the liver than the AST value because the AST value may also be high if there is muscle damage elsewhere in the body.
Apr 20, 2021 · Reference ranges. Male: Less than 50 U/L. Female: Less than 35 U/L. Significantly raised ALT (> 3 x ULN) or persistently mildly raised ALT (for 3 - 6 months) should be further investigated.
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The normal range for alanine transaminase (ALT) varies from laboratory to laboratory. One common reference range for an ALT blood test is 7 to 56 U/L (units per liter). ALT levels are typically higher in people assigned male at birth than in people assigned female at birth.