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  1. The central idea is that universality of the genetic code is a condition for maintaining the (horizontal) flow of genetic information between communities of primordial replicators, and this information flow is a condition for the evolution of any complex biological entities.

    • Eugene V. Koonin, Artem S. Novozhilov
    • 10.1002/iub.146
    • 2009
    • 2009/02
  2. Dec 31, 2008 · The three main concepts on the origin and evolution of the code are the stereochemical theory, according to which codon assignments are dictated by physicochemical affinity between amino acids and the cognate codons (anticodons); the coevolution theory, which posits that the code structure coevolved with amino acid biosynthesis pathways; and the...

    • Eugene V. Koonin, Artem S. Novozhilov
    • 244
    • 2009
    • 31 December 2008
  3. en.wikipedia.org › wiki › 23_enigma23 enigma - Wikipedia

    In these works, 23 is considered lucky, unlucky, sinister, strange, sacred to the goddess Eris, or sacred to the unholy gods of the Cthulhu Mythos. The 23 enigma can be viewed as an example of apophenia, selection bias and confirmation bias.

  4. Jan 22, 2009 · The arrows define 13 precursor-product pairs of amino acids, their color defines the biosynthetic families of Glu (blue), Asp (dark-green), Phe (magenta), Ser (red), and Val (light-green). See Origin and Evolution of the Genetic Code: The Universal Enigma by Koonin and Novozhilov, pp. 99-111.

    • Eugene V. Koonin, Artem S. Novozhilov
    • 2009
  5. Mar 11, 2016 · Here we give an overview of a worldwide effort, called the ENIGMA Consortium (http://enigma.ini.usc.edu), which unites scientists worldwide to determine how variants in our genetic code influence the brain, and how 12 major diseases affect the brain worldwide.

    • 10.1007/978-3-319-27777-6_10
    • 2016/03/11
  6. Mar 20, 2020 · Building on large-scale genetic studies that discovered the first robustly replicated genetic loci associated with brain metrics, ENIGMA has diversified into over 50 working groups (WGs), pooling...

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  8. Sep 26, 2015 · 1. Introduction. A number of major characteristics distinguish the genomes of eukaryotes from those of ‘prokaryotes’ (Bacteria and Archaea). Of course, the most obvious (and defining) difference is the separation of the genome from the cytoplasm by the presence of a nuclear membrane.

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