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Over 17 million children are affected by severe acute malnutrition (SAM) worldwide. Despite significant progress in recent years, approximately 2.9 million children accessed treatment in 65 countries in 2013 – only about 17 percent of the children needing treatment. Children with SAM are nine times more likely to die than well-nourished children.
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preventable, might not improve.5 Finally, evidence and care are constantly changing. What is considered inevitable harm today could in fact be preventable in five years. Definitions of preventable harm need to be continually updated. Better measurement Firstly, it is important to capture all potential risks to patient safety, not just adverse ...
- Irene Papanicolas, Jose F Figueroa
- 2019
Jul 7, 2021 · Go to: Highlights. Three licensed SMA therapies increase SMN levels, but are not a cure. Other strategies to increase SMN levels are still under development. Alternatives target the correction of dysregulated pathways following SMN loss. Ultimately, a range of therapies may allow for a tailored treatment.
- Helena Chaytow, Kiterie M.E. Faller, Yu-Ting Huang, Thomas H. Gillingwater
- 10.1016/j.xcrm.2021.100346
- 2021
- Cell Rep Med. 2021 Jul 20; 2(7): 100346.
Jul 17, 2019 · Yet no consensus exists as to what constitutes preventable harm, and even experienced clinicians vary in the extent to which they agree on whether an error is preventable. 3 Panagioti and colleagues define preventable harm as the result of an identifiable modifiable cause and an event the recurrence of which can be avoided by the adaptation of a...
- Irene Papanicolas, Jose F Figueroa
- 2019
- Severe Acute Malnutrition: Local vs. Imported RUTF
- Severe and Moderate Acute Malnutrition: Inpatient vs. Ambulatory Care
- Results from Additional Studies Not Included in Meta-Analysis
Two trials, one in Senegal, graded as low quality and the other in Malawi, graded as moderate quality , compared imported RUTF to locally produced RUTF used in community-based management of SAM. There was no significant difference in weight gain between intervention groups (figure 8). This effect was consistent (I2= 0%) and the overall outcome was...
Two studies compared home-based treatment to inpatient treatment in children without severe complications. One moderate quality study in Niamey, Niger, enrolled children with MAM and SAM who were about to be discharged from the hospital . The other study, graded as low quality, allocated children presenting to the nutrition unit in Dhaka, Banglades...
We identified several interesting singular studies that could not be pooled in the meta-analysis. Oakley et al. studied the effect of an RUTF consisting of 25% milk versus another with 10% milk in treating children with SAM, and found that the RUTF with the higher milk content was associated with a statistically significant higher recovery rate (p...
- Lindsey M Lenters, Kerri Wazny, Patrick Webb, Tahmeed Ahmed, Zulfiqar A Bhutta
- 2013
Abstract. Severe acute malnutrition (SAM) affects approximately 13 million children under the age of 5 and is associated with 1-2 million preventable child deaths each year. In most developing countries, case fatality rates (CFRs) in hospitals treating SAM remain at 20-30% and few of those requiring care actually access treatment.
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May 25, 2012 · The three most prevalent preventable harms in the included studies were: medication adverse events (33/127 studies, 26%), central line infections (7/127, 6%) and venous thromboembolism (5/127, 4%). Seven themes or definitions for preventable harm were encountered.
