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  2. Feb 10, 2023 · Pain happens, but when it sticks around for a long period of time or feels unbearable, nonaddictive pain medication may sound like a safer alternative to opioids. Most people have experienced...

  3. Apr 7, 2020 · Unfortunately, there aren’t many substitutes for opioids like tramadol, as tramadol has a different mechanism of action than most other substitutes. Therefore, you should always discuss your options with your doctor in great detail to determine the best way to manage your pain.

  4. Nov 21, 2022 · According to the Health Resources and Services Administration (HRSA), opioid-related overdoses cause more than 130 deaths every day. Fortunately, there are non-opioid alternatives that are effective for managing chronic pain. This article discusses chronic pain, opioid use, and alternative treatments.

  5. “For the past couple of decades, prescription opioids such as oxycodone, hydrocodone, codeine, and morphine have been popular choices for helping patients to manage acute pain,” says Dr....

    • Acetaminophen. Acetaminophen, the active ingredient in Tylenol, is an over-the-counter (OTC) medication that’s good for relieving headaches, back pain, and arthritis pain.
    • NSAID pills. NSAIDs (nonsteroidal anti-inflammatory drugs) are great for treating mild to moderate pain, such as pain from muscle injury, inflammation (swelling), arthritis, and back issues.
    • Celebrex. A newer NSAID, celecoxib (Celebrex), is available by prescription only. Celebrex is a COX-2 inhibitor medication. It works well as a painkiller and an anti-inflammatory medication.
    • NSAID gels, liquids, patches, and creams. NSAIDs are also available as topical products, like anti-inflammatory creams. These can help with some types of pain, particularly when the pain is centered around a joint or in a specific area of the body.
  6. Feb 17, 2023 · Two common examples include pain relief due to musculoskeletal conditions or abdominal pain related to conditions such as inflammatory bowel disease. Some common corticosteroids include ...

  7. Oct 26, 2022 · Drugs such as dexmedetomidine that bind to the norepinephrine alpha-2a (α2a) adrenergic receptor are effective analgesics, but their sedative effects limit their widespread use. A recent...

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