Search results
medicalnewstoday.com
- Includes a heterogeneous group of diseases, characterised by inflammation and necrosis of blood vessel walls. Presenting features may include fever, weight loss, fatigue, multi-system involvement (skin, nasal bleeding/crusting, arthralgia, myalgia, neuropathy), with raised inflammatory markers and abnormal urinalysis.
www.labmed.heartofengland.nhs.uk/advice/immunology-clinical-advice-and-test-interpretation/20-connective-tissue-disease-and-vasculitis.html
People also ask
What causes large vessel vasculitis in adults?
What is a connective tissue disease?
What is systemic vasculitis?
What is vasculitis immunology?
Sep 27, 2022 · To provide a comprehensive overview of the spectrum of large and medium vessel vasculitis in adults with primary vasculitides, arthritides, connective tissue, and fibroinflammatory diseases as well as vasculitis mimics, for an efficient differential diagnosis and initial diagnostic approach.
- Table1 1
National Center for Biotechnology Information
- Pulmonary Disease in Polymyositis/Dermatomyositis
Pulmonary vasculitis was seen in five patients; pulmonary...
- Polyarteritis Nodosa and Mixed Cryoglobulinaemia Related to Hepatitis B and C Virus Coinfection
CASE REPORT—The case of a 38 year old woman who had a past...
- Evolution of Laboratory Values in Patients With Kawasaki Disease
Kawasaki disease (KD), the leading cause of pediatric...
- Late Onset Takayasu Arteritis and Rheumatoid Arthritis
Takayasu arteritis (TA) is a rare, chronic vasculitis of...
- Table1 1
The term vasculitis refers to inflammation of blood vessels and represents a heterogeneous group of clinical disorders. Each form of vasculitis can produce a distinct clinical picture, but in many cases immunology testing can differentiate, confirm and monitor the presence of vasculitis.
Vasculitis can be a primary disorder or secondary to other causes. Vasculitis tends to affect small-, medium-, or large-sized vessels, each with certain patterns of organ involvement. Clinical manifestations can be systemic and/or organ-specific, depending on how vessels are affected.
- Alexandra Villa-Forte
- Overview
- Symptoms and Causes
- Diagnosis and Tests
- Management and Treatment
- Prevention
- Outlook / Prognosis
- Living With
Your body is held together by tissues that connect all of the structures in your body. When you have a connective tissue disease, these connecting structures are negatively affected. Connective tissue diseases include autoimmune diseases like rheumatoid arthritis, scleroderma and lupus.
Contents
Arrow Down
OverviewSymptoms and CausesDiagnosis and TestsManagement and TreatmentPreventionOutlook / PrognosisLiving With
Contents
Arrow Down
What causes connective tissue diseases?
These conditions can be caused by family genetics and are often known as heritable disorders of connective tissue. Connective tissue diseases can also be caused by things that exist in the environment. Non-inherited causes of autoimmune types of connective tissue disease may include: Exposure to toxic chemicals, such as those found in air pollution and cigarette smoke. Exposure to ultraviolet light. Inadequate nutrition, including lack of vitamins D and C. Infections. Advertisement
What are the symptoms of connective tissue diseases?
Because there are so many different kinds of connective tissue diseases, symptoms may vary and may affect different parts of the body. Body parts that may be affected include: Bones. Joints. Skin. Heart and blood vessels. Lungs. Some of the diseases, like the ones mentioned above, can cause serious pulmonary issues. Head and face. Some of these diseases can make the face, head, eyes and ears look different than the faces and heads of other people. Height. Some diseases cause the people who have them to be very tall or very short.
How are connective tissue diseases diagnosed?
Your doctor may order various tests depending on what type of connective tissue disorder is suspected. The doctor will first ask for your medical history, a family history, and will do a physical examination. Further tests may include: Imaging tests, such as X-rays and magnetic resonance imaging (MRI) scans. Tests for markers of inflammation, such as C-reactive protein and Erythrocyte sedimentation rate (ESR). Tests for antibodies, especially for autoimmune conditions. Tests for dry eyes or dry mouth. Blood and urine tests. Tissue biopsy. Advertisement
How are connective tissue diseases treated?
Because there are so many different types of connective tissue disorders, the treatments will vary depending on the person and the disease. Treatments might include vitamin supplements, physical therapy, and medications. You will probably have a regular schedule of appointments with your doctor. You might be asked to consult with specialists, such as eye doctors or dermatologists, depending on what type of connective tissue disorder you have. Care at Cleveland Clinic Rheumatology Care for Adults Rheumatology Care for Children Make an Appointment
Can you prevent connective tissue diseases?
You may be able to prevent exposures to toxins, and you are able to eat healthy foods that meet your vitamin and nutrient needs. However, you cannot prevent diseases that are inherited.
What is the outlook (prognosis) for people who have connective tissue diseases?
The outlook for people with connective tissue diseases is different for everyone. The outlook depends on what type of disease you have, whether or not you get treatment, and how effective the treatment is. Some types of connective tissue diseases may have relatively minor consequences, and some can be fatal (if they affect the lungs, kidneys or heart.) Some types of these diseases are painful, while others have more mild symptoms. You may be asked to make some lifestyle changes. Also, you may be asked to get vaccines for the flu or vaccine for pneumonia (when your connective tissue disease is in remission).
When should you contact your doctor if you have a connective tissue disease?
You should contact your healthcare provider if you have new or worsening symptoms, including: Skin changes, such as changes in color or texture. Vision changes. Pain. Feeling sick. Muscle weakness. You should keep the schedule of appointments that your healthcare provider suggests. Medically Reviewed Last reviewed by a Cleveland Clinic medical professional on 12/16/2019. Learn more about our editorial process.
Systemic sclerosis or scleroderma is a rare disease that is characterised by widespread inflammation and fibrosis. The hallmark of the disease is thickened skin (sclera=thick, derma=skin). It ranges from limited, to diffuse and in rare cases can lead to complications such as pulmonary hypertension. Almost all patients with
- 41KB
- 2
Aug 15, 2007 · Systemic vasculitis, an inflammatory necrotizing disease of the blood vessel walls, can occur secondary to autoimmune diseases, including connective tissue diseases. Various pathogenic mechanisms have been implicated in the induction of vasculitis, including cell-mediated inflammation, immune complex-mediated inflammation and autoantibody ...
Oct 14, 2016 · Vasculitis is a recurrent complication of connective tissue diseases. It is often an under-recognized manifestation that can lead to significant morbidity and mortality due to vital organ damage. Cutaneous lesions, representing small-vessel vasculitis, dominate...
