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High Purity. Fibronectin Protein, Expressed in HEK293. With C-His Tag. For Protein Structure & Function Research. 30,000+ Citations
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soluble plasma fibronectin (formerly called "cold-insoluble globulin", or CIg) is a major protein component of blood plasma(300 μg/ml) and is produced in the liverby hepatocytes. insoluble cellular fibronectin is a major component of the extracellular matrix.
Apr 3, 2024 · FN1 (Fibronectin 1) is a Protein Coding gene. Diseases associated with FN1 include Spondylometaphyseal Dysplasia, Corner Fracture Type and Glomerulopathy With Fibronectin Deposits 2. Among its related pathways are Signaling downstream of RAS mutants and Integrin Pathway.
Jun 19, 2020 · Here we report that fibronectin 1 (FN-1) promoted differentiation and mineralization of osteoblasts by activating WNT/β-catenin pathway, in cultured pre-osteoblasts. With isobaric tags for...
- Chengliang Yang, Chong Wang, Jing Zhou, Qingyang Liang, Feng He, Feng Li, Ye Li, Jinzhong Chen, Fan ...
- 2020
Aug 23, 2022 · Fibronectin 1 (FN1) is a glycoprotein found throughout the extracellular matrix that has a role in the onset and progression of cancer. However, its immune relationship with gastric cancer is still unclear.
FN1 mutations that cause defective fibronectin secretion are found in SMD. FN1 overexpression is an important determinant of thyroid cancer aggressiveness. Thyroid hormone T3 induces fibronectin and HIF-1alpha synthesis via PI3K/AKT signaling pathway.
The FN1 gene encodes two types of fibronectin-1 protein, which are involved in blood clotting, wound healing, tissue repair and cell migration. Learn about the normal function, genetic changes and health conditions related to the FN1 gene, as well as additional information and resources.
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Jun 17, 2024 · This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. The encoded preproprotein is proteolytically processed to generate the mature protein.
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Crude Overexpression Lysate and Purified Proteins are Both Available. Purified from Mammalian cells. Near native structure & PTMs. In Stock. Order Now!
