Search results
People also ask
Where are arterial baroreceptors located?
How does a baroreceptor control blood pressure?
What are the different types of baroreceptors?
What is the function of arterial baroreceptors?
Mar 6, 2023 · There are two types of baroreceptors: high-pressure arterial baroreceptors and low-pressure volume receptors, which are both stimulated by stretching of the vessel wall. Arterial baroreceptors are located within the carotid sinuses and the aortic arch.
- 2023/03/06
- Introduction
- Rapid Control of Blood Pressure
- Intermediate and Long-Term Regulation of Bp
- Other Regulators of Blood Pressure
- How Do Vasoactive Compounds Change SVR and BP?
- Key Points
- References
Blood pressure (BP) can provide insight into the workings of the heart and vessels of the body. BP is controlled by a variety of complex physiological mechanismswhich allow both short-term adaptation and longer-term maintenance of BP within a normal range. Blood pressure which is too high or too low can lead to a wide range of pathology (e.g. ruptu...
Baroreceptor reflex
The baroreceptor reflexis a neurally-mediated reflex that regulates blood pressure in the short term. This reflex is crucial for maintaining blood pressure throughout the day, and in its absence, even a slight change in posture could lead to significant changes in blood pressure. There are mechanoreceptors known as baroreceptors located in the aortic arch and carotid sinus, which constantly monitor the MABP and pulse pressure.1 Increases in arterial pressure result in increased baroreceptor a...
Renin-angiotensin-aldosterone system
The renin-angiotensin-aldosterone system (RAAS) is an essential component of blood pressure regulation that acts to increase blood volume and increase systemic vascular resistance.1 This system is dependent on hormonal changes which induce transcription of genes to produce vasoactive proteins, making it aslower means of controlling blood pressure than the baroreceptor reflex.3 The RAAS system starts with renin, a hormone released from granular cells in the juxtaglomerular apparatus, a special...
Antidiuretic hormone
Antidiuretic hormone, also known as vasopressin, is involved in the control of blood pressure. ADH is made by cell bodies located in the hypothalamus and released from the adjacent posterior pituitary.1,6 The following physiological changes trigger ADH release: 1. an increase in plasma osmolarity (detected by osmoreceptors in the hypothalamus) 2. a reduction in blood volume 3. an increase in the levels of angiotensin II ADH increases water reabsorption by binding to V2 receptors, subsequently...
Low-pressure baroreceptors
Low-pressure baroreceptors, in contrast to the high-pressure baroreceptors discussed previously, are found in the venous system, atria and pulmonary arteries.3 They respond to changes in plasma volume, modulating blood pressure via various mechanisms.
Atrial natriuretic peptide
Atrial natriuretic peptide (ANP) is a vasoactive peptide released from the atria in response to a rise in atrial pressures, which in turn are linked to venous pressure.6 ANPlowers blood pressure, primarily by vasodilation and the inhibition of sodium reabsorption by the kidney, the latter having a diuretic effect.1.3 This systemincreases sodium excretion in part through the opposition of the renin-angiotensin-aldosterone system, inhibiting renin and aldosterone release.1 ANP has also been sho...
Vasoactive compounds often modify the amount of resistance in the systemic circulation (systemic vascular resistance – SVR) by targeting arterioles, the smallest arterial vessels. The smooth muscle in these vessels contains several receptors, which when bound to, give rise to either of the following responses, depending on receptor type: 1. Stimula...
Blood pressure regulation is a complex process, regulated by several mechanisms that work in unison to maintain homeostasis.Rapid adjustments in blood pressure are typically neurally mediated by the baroreceptor reflex.Intermediate and long term regulation of blood pressure is predominantly mediated by vasoactive compounds.Sherwood L. Human Physiology: From Cells to Systems – 9thEdition. Published in 2016. Available from Cengage Learning.Mulroney S, Myers A, Netter FH, Machado CA, Craig JA, Perkins JA. Netter’s Essential Physiology. Published in 2009. Available from Elsevier Inc.Costanzo LS. Physiology- 6thEdition. Published in 2018. Available from Elsevier.Unknown author. Histology @ Yale: Juxtaglomerular apparatus. Available from: [LINK]There are two types of baroreceptors: High-pressure arterial baroreceptors and low-pressure volume receptors which are both stimulated by stretching of the vessel wall. Arterial baroreceptors are located within the carotid sinuses and the aortic arch.
Baroreceptors can be divided into two categories based on the type of blood vessel in which they are located: high-pressure arterial baroreceptors and low-pressure baroreceptors (also known as cardiopulmonary or volume receptors).
Arterial baroreceptors are located in high-pressure regions, namely in the aortic arch, and the carotid bodies, whereas cardiovascular baroreceptors are located within the heart's atria, ventricles, and pulmonary vessels.
This is accomplished by negative feedback systems incorporating pressure sensors (i.e., baroreceptors) that sense the arterial pressure. The most important arterial baroreceptors are in the carotid sinus (at the bifurcation of external and internal carotids) and in the aortic arch (Figure 1).
Baroreceptors are stretch-sensitive mechanoreceptors in the walls of the aortic arch and carotid sinus that monitor blood pressure by responding to changes in the tension of the arterial wall. Stretch activates them.
