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1. www.nhs.uk › conditions › granulomatosis-withGranulomatosis with polyangiitis (GPA) - NHS

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   Granulomatosis with polyangiitis (GPA) is a type of vasculitis, which is an inflammation of the blood vessels. Symptoms vary between people, and can be mild or severe. In some people, they come on slowly over many months, and in others they appear suddenly.

2. www.nhs.uk › peripheral-arterial-disease-padPeripheral arterial disease (PAD) - NHS

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   Mar 20, 2023 · Peripheral arterial disease (PAD) is a common condition where a build-up of fatty deposits in the arteries restricts blood supply to leg muscles. It's also known as peripheral vascular disease (PVD). Symptoms of peripheral arterial disease. Many people with PAD have no symptoms.

3. www.mayoclinic.org › diseases-conditions › granuloGranulomatosis with polyangiitis - Symptoms and causes

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   • Overview
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   Granulomatosis with polyangiitis is an uncommon disorder that causes inflammation of the blood vessels in your nose, sinuses, throat, lungs and kidneys. Formerly called Wegener's granulomatosis, this condition is one of a group of blood vessel disorders called vasculitis. It slows blood flow to some of your organs. The affected tissues can develop ...

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   Signs and symptoms of granulomatosis with polyangiitis can develop suddenly or over several months. The first warning signs usually involve your sinuses, throat or lungs. The condition often worsens rapidly, affecting blood vessels and the organs they supply, such as the kidneys. Signs and symptoms of granulomatosis with polyangiitis might include:...

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   The cause of granulomatosis with polyangiitis isn't known. It's not contagious, and there's no evidence that it's inherited. The condition can lead to inflamed, narrowed blood vessels and harmful inflammatory tissue masses (granulomas). Granulomas can destroy normal tissue, and narrowed blood vessels reduce the amount of blood and oxygen that reach...

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   Granulomatosis with polyangiitis can occur at any age. It most often affects people between the ages of 40 and 65.

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   Besides affecting your nose, sinuses, throat, lungs and kidneys, granulomatosis with polyangiitis can affect your skin, eyes, ears, heart and other organs. Complications might include: 1. Hearing loss 2. Skin scarring 3. Kidney damage 4. A loss of height in the bridge of the nose (saddling) caused by weakened cartilage 5. A blood clot forming in on...

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4. www.vasculitis.org.uk › about-vasculitis › gpa-granuGranulomatosis with Polyangiitis (GPA) - Vasculitis UK

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   What are the symptoms? The disease can present in very different ways in different people depending on the severity and the organs involved. It is not uncommon for patients to have had mild symptoms for months or even years before seeing a doctor at all.

5. www.bhf.org.uk › informationsupport › conditionsVentricular septal defect (VSD) - BHF - British Heart Foundation

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   being underweight and growing slowly. irregular or extra heart beats, called arrhythmias. Adults with a VSD may also have signs and symptoms, such as: shortness of breath, especially when exercising. you may not be able to exercise for long. feeling very tired. irregular or extra heart beats, called arrhythmias.

6. my.clevelandclinic.org › health › diseasesGranulomatosis with Polyangiitis (GPA, formerly called Wegener’s)

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   Symptoms may include: Persistent runny nose (also called rhinorrhea) or the formation of nasal crusts and sores. Nasal or facial pain. Nose bleeds or unusual nasal discharge, caused by inflammation of the nose or sinuses. Cough that might include bloody phlegm caused by upper airway or lower airway (lung) inflammation.

7. People also ask

   How do I know if I have heart valve disease?

   • The most common test to diagnose heart valve disease is an echocardiogram. There are different types of echocardiogram, you may have one or more. You may also have other tests or scans, such as: angiogram. Ask your doctor about the tests they’re recommending you have. They can answer any questions or concerns.

   Heart valve disease - BHF

   www.bhf.org.uk/informationsupport/conditions/heart-valve-disease

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   What is heart valve disease?

   • Heart valve disease is when one or more of your heart valves do not work like they should. There are several types of heart valve disease. The main problems are caused by the valve not opening fully or the valve not closing properly. Valve stenosis or narrowing means the valve does not open fully, it can block or restrict the flow of blood.

   Heart valve disease - BHF

   www.bhf.org.uk/informationsupport/conditions/heart-valve-disease

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   What are the symptoms of peripheral vascular disease (PVD)?

   • It's also known as peripheral vascular disease (PVD). Many people with PAD have no symptoms. However, some develop a painful ache in their legs when they walk, which usually disappears after a few minutes' rest. The medical term for this is "intermittent claudication".

   Peripheral arterial disease (PAD) - NHS

   www.nhs.uk/conditions/peripheral-arterial-disease-pad/

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   How do you know if you have vasculitis?

   • Other common symptoms include: Bowels – Diarrhoea, bleeding and abdominal pain. As in other types of vasculitis there is no single test which confirms the diagnosis. The diagnosis will depend on the doctor recognising the pattern of symptoms and examination findings. Blood tests usually show evidence of inflammation.

   Granulomatosis with Polyangiitis (GPA) - Vasculitis UK

   www.vasculitis.org.uk/about-vasculitis/gpa-granulomatosis-with-polyangiitis

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8. www.bhf.org.uk › conditions › heart-valve-diseaseHeart valve disease - BHF

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   Symptoms of heart valve disease. Some people with heart valve disease have no symptoms. Other people may have one or more symptoms. Doctors may hear a heart murmur (a swishing sound) when they listen to your heart with a stethoscope. This could be a sign that you have a heart valve problem. Common symptoms of heart valve disease are: feeling ...