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Dec 12, 2019 · The Allred score combines the percentage of positive cells and the intensity of the reaction product in most of the carcinoma. The 2 scores are added together for a final score with 8 possible values. Scores of 0 and 2 are considered negative. Scores of 3-8 are considered positive. H Score for Estrogen and Progesterone Receptor Evaluation.
- Allred
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- Allred
Nov 16, 2022 · Allred score Summation of proportion (0 - 5) and intensity (0 - 3) of ER positive tumor cells into a score of 0 to 8 out of 8 Proportion 0: 0% 1: 1% 2: 1 - 10% 3: 11 - 33% 4: 34 - 66% 5: > 66% Intensity 0: negative 1: weak 2: moderate 3: strong Scores 0 and 2 interpreted as negative; scores 3 to 8 interpreted as positive. H score
Dec 8, 2022 · The 2 scores are then added together for a final score with 8 possible values (the Allred score). Allred scores of 0 and 2 are considered negative for ER (i.e., not actionable), while scores of 3 to 8 are considered positive (i.e., recommended for hormonal therapy). Note that a score of 1 is not a possible outcome.
- 10.3390/diagnostics12123093
- 2022/12
- Diagnostics (Basel). 2022 Dec; 12(12): 3093.
Allred or H-score measures have remained associated with survival-related outcomes in multivariate models in a number of studies, possibly due to inclusion of ER intensity as a component [8,5,12]. The correlation between good prognosis tumor characteristics and increasing ER positivity that we identified also has been noted in a number of investigations [ 29 , 8 , 30 , 25 ].
- Deirdre A. Hill, Marc Barry, Charles Wiggins, Andrea Nibbe, Melanie Royce, Eric Prossnitz, Lesley Lo...
- 10.1007/s10549-017-4439-6
- 2017
- 2017/12
Aug 10, 2019 · A shortcoming of the Allred scoring system exists, since some of the possibilities for the final score are only hypothetical (3 + 0, 4 + 0, and 5 + 0) (Table 1). One may say that our study overcomes such shortcomings based on the strong positive correlation between the quantitative nuclear stain intensity and the percent of ER-positive nuclei ( Figure 5 , down).
- Ivan R Ilić, Nikola M Stojanović, Niko S Radulović, Vesna V Živković, Pavle J Randjelović, Aleksanda...
- 10.3390/medicina55080461
- 2019
- Medicina (Kaunas). 2019 Aug; 55(8): 461.
May 30, 2018 · A clinical example of this type of composite score is the Allred score, ... or to calculate relevant tissue parameters such as cell or staining per area ... What brown cannot do for you. Nat ...
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their Allred /Quickscore. Reports should include the overall percentage of positive cells and the average intensity regardless of whether additional scoring systems, such as Allred or H score, are also reported. All cases showing <1% of tumour cells positive should be classified as receptor negative regardless of their Allred score.
