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    upstream
    /ˌʌpˈstriːm/

    adverb

    • 1. in the opposite direction from that in which a stream or river flows; nearer to the source: "a lone motor cruiser rumbled upstream"
    • 2. in or towards the part of a sequence of genetic material where transcription takes place earlier than at a given point.

    adjective

    • 1. moving or situated in the opposite direction from that in which a stream or river flows: "the upstream stretch of the river"
    • 2. situated in or towards the part of a sequence of genetic material where transcription takes place earlier than at a given point.

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