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Dec 12, 2019 · The Allred score combines the percentage of positive cells and the intensity of the reaction product in most of the carcinoma. The 2 scores are added together for a final score with 8 possible values. Scores of 0 and 2 are considered negative. Scores of 3-8 are considered positive.
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Dec 8, 2022 · Allred scores of 0 and 2 are considered negative for ER (i.e., not actionable), while scores of 3 to 8 are considered positive (i.e., recommended for hormonal therapy). Note that a score of 1 is not a possible outcome.
- 10.3390/diagnostics12123093
- 2022/12
- Diagnostics (Basel). 2022 Dec; 12(12): 3093.
The Allred score is based on an assessment of the percentage/proportion of tumor cells in a histopathologic specimen that stain positively and the intensity of the staining.
Nov 16, 2022 · Definition / general. The most clinically important hormone receptors in breast cancer are estrogen, progesterone, and to a lesser extent, androgen receptors. Hormone receptor status is strongly associated with histology, prognosis and treatment response. Essential features.
Dec 8, 2022 · The system first detects all cells within the specific regions and classifies them into negatively, weakly, moderately, and strongly stained, followed by Allred scoring for ER status evaluation. The generated Allred score relies heavily on accurate cell detection and classification and is compared against pathologists’ manual estimation.
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What is the Allred score?
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